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Table 3 The top 10 immune-related KEGG pathways with the highest number of co-expressed DEGs

From: Transcriptomic analysis of sea cucumber (Holothuria leucospilota) coelomocytes revealed the echinoderm cytokine response during immune challenge

Pathway IDDEGs annotation in the pathwayAll genes annotation in the pathwayP-valuesPathway annotation
ko0461016 (4.1%)84 (0.55%)3.141596e-10Complement and coagulation cascades
ko0465815 (3.85%)218 (1.43%)0.0004926241Th1 and Th2 cell differentiation
ko046507 (1.79%)115 (0.75%)0.02799556Natural killer cell mediated cytotoxicity
ko0461110 (2.56%)213 (1.39%)0.04710404Platelet activation
ko046709 (2.31%)208 (1.36%)0.08609158Leukocyte transendothelial migration
ko046667 (1.79%)155 (1.01%)0.102463Fc gamma R-mediated phagocytosis
ko046205 (1.28%)118 (0.77%)0.1839742Toll-like receptor signaling pathway
ko046594 (1.03%)88 (0.58%)0.1874437Th17 cell differentiation
ko040627 (1.79%)188 (1.23%)0.2058452Chemokine signaling pathway
ko046575 (1.28%)127 (0.83%)0.2245483IL-17 signaling pathway