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Table 3 Color-associated genes with SNPs showing signatures of directional selection among the three color phenotypes of O. pumilio studied

From: Being red, blue and green: the genetic basis of coloration differences in the strawberry poison frog (Oophaga pumilio)

SNP alleles q-value alpha Fst gene Link to pigmentation
pasa_150225:833 C/T 0.042 1.396 0.447 mpzl3_2 severe skin and hair abnormalities in mice (p)
pasa_255433:3485 G/A 0.032 1.623 0.498 fzd6_1 melanin synthesis (p)
pasa_343423:2249 C/A 0.002 1.916 0.561 hba2 hyperpigmented human skin
pasa_343423:2449 A/G 0.002 1.940 0.567 hba2 hyperpigmented human skin
pasa_394127:2961 C/T 0.046 1.387 0.445 med1 retinal pigmentation
pasa_398461:1237 G/A 0.006 1.795 0.535 rxrb_1 carotenoid metabolism (p)
pasa_45399:7303 C/T 0.018 1.718 0.518 unc119 retinal pigmentation
pasa_533653:4303 G/A 0.002 1.935 0.566 kit melanin synthesis
pasa_533653:4362 A/T 0.003 1.922 0.563 kit melanin synthesis
pasa_533653:4575 G/A 0.002 1.919 0.562 kit melanin synthesis
pasa_533653:5276 A/C 0.002 1.935 0.565 kit melanin synthesis
pasa_534292:953 G/A 0.007 1.755 0.526 rdh12_3 carotenoid metabolism (p)
  1. For each SNP entry, the position and alternative alleles, as well as BayeScan results (posterior probability, q-value, alpha, Fst) are presented along with the gene symbol and potential link to pigmentation. Gene symbols followed by underscore and a number represent potential paralogs and their functions (p) are less reliable