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Table 1 Genes Associated with Peroxide Resistance

From: The metabolome as a link in the genotype-phenotype map for peroxide resistance in the fruit fly, Drosophila melanogaster

FlyBase ID

Gene

Name

Lead Variant

Pmin

Pgene

FDR

FBgn0031803

ppk14

Pickpocket 14

2L_6353972_SNP

2.12 × 10–6

9.00 × 10–6

0.004797

FBgn0031261

nAChRbeta3

Nicotinic acetylcholine receptor beta 3 (Dbeta3) subunit

2L_544231_SNP

9.73 × 10–7

2.20 × 10–5

0.011704

FBgn0031802

ppk7

Pickpocket 7

2L_6351358_SNP

2.12 × 10–6

2.70 × 10–5

0.014337

FBgn0034098

krimp

FI20010p1

2R_12124705_SNP

1.68 × 10–6

3.10 × 10–5

0.01643

FBgn0034099

CG15708

AT21920p

2R_12127442_SNP

1.68 × 10–6

3.10 × 10–5

0.01643

FBgn0005660

Ets21C

DNA-binding protein D-ETS-6

2L_546065_SNP

9.73 × 10–7

3.30 × 10–5

0.017424

FBgn0002031

l(2)37Cc

Protein l(2)37Cc

2L_19121067_SNP

7.57 × 10–6

4.50 × 10–5

0.023715

FBgn0003963

ush

Zinc finger protein ush

2L_475238_SNP

4.51 × 10–8

7.10 × 10–5

0.037346

FBgn0031865

Nha1

Na[+]/H[+] hydrogen antiporter 1, isoform A

2L_6860010_SNP

5.32 × 10–8

0.000123

0.064575

FBgn0020906

Jon25Bi

Jonah 25Bi

2L_4953449_SNP

4.23 × 10–5

0.000214

0.112136

FBgn0031655

Marcal1

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1

2L_4954910_SNP

1.27 × 10–5

0.000253

0.132319

FBgn0263831

Gen

Flap endonuclease GEN

3L_5141974_SNP

7.43 × 10–6

0.000262

0.136764

FBgn0037730

DmelCG9444

CG9444, isoform A

3R_5506170_SNP

9.71 × 10–5

0.000272

0.141712

FBgn0005616

msl-2

E3 ubiquitin-protein ligase msl-2

2L_3461213_SNP

3.65 × 10–5

0.000367

0.19084

FBgn0263102

psq

Pipsqueak, isoform M

2R_6444567_SNP

3.29 × 10–5

0.000373

0.193587

FBgn0004103

Pp1-87B

Serine/threonine-protein phosphatase alpha-2 isoform

3R_8248858_SNP

0.0001966

0.000437

0.226366

FBgn0083960

DmelCG34124

FI23230p1

2L_4957415_SNP

1.27 × 10–5

0.000461

0.238337

FBgn0040510

ACXA

Adenylyl cyclase X, isoform A

2L_12920145_SNP

5.17 × 10–5

0.000472

0.243552

FBgn0085227

CG34198

HDC07368

2R_15569059_SNP

0.0001068

0.000489

0.251835

FBgn0040506

ACXE

Adenylyl cyclase X, isoform E

2L_12924675_SNP

8.53 × 10–5

0.000517

0.265738

FBgn0027109

NPF

Neuropeptide F

3R_12434359_SNP

9.19 × 10–5

0.000578

0.296514

FBgn0031538

DmelCG3246

CG3246

2L_3459329_SNP

3.65 × 10–5

0.000611

0.312832

FBgn0052391

DmelCG32391

Uncharacterized protein

3L_7060319_SNP

1.15 × 10–5

0.000723

0.369453

FBgn0038043

CG17202

c-Myc-binding protein homolog

3R_8247496_SNP

0.0001966

0.000762

0.38862

FBgn0005640

Eip63E

Ecdysone-induced protein 63E, isoform N

3L_3514849_SNP

1.80 × 10–5

0.00091

0.46319

FBgn0051641

stai

stathmin

2L_6099379_SNP

6.01 × 10–6

0.000922

0.468376

FBgn0014009

Rab2

GH01619p

2R_2583312_SNP

5.43 × 10–5

0.000932

0.472524

FBgn0262467

Scox

AT19154p

2L_4967292_SNP

0.0002591

0.000943

0.477158

FBgn0040509

ACXB

Adenylyl cyclase X, isoform B

2L_12916421_SNP

0.0003891

0.00096

0.4848

  1. The gene identifications from Fly Base (FB) release 5.49 for all genes with Pgene FDR < 0.5. The variant with the smallest P value for each gene (Pmin) is listed as the lead variant