Table 3 DMGs most likely involved in muscle development

Gene name

FPKM of Fetus

FPKM of Adult

log2FC

MethChr

MethDiff (FetusV Adult)

P-value

Annotation

ADIPOQ

2.7 ± 0.70

59.02 ± 8.37

5.07

1 (198577572–198,577,648)

0.355

1.95E-13

Distal Intergenic

CCNA2

3.96 ± 1.32

0.22 ± 0.04

−3.53

6 (3651607–3,651,817)

0.494

8.16E-19

Intron

ITGA1

6.3 ± 2.32

0.22 ± 0.06

−4.20

16 (26099670–26,099,819)

−0.374

1.02E-08

Intron

MYOG

118.2 ± 11.46

8.76 ± 1.99

−3.15

12 (196054–196,192)

−0.409

2.76E-07

Exon

12 (220130–220,377)

−0.314

4.32E-09

Distal Intergenic

12 (229114–229,232)

0.54

7.28E-07

Distal Intergenic

MAPT

1.08 ± 0.27

6.49 ± 1.04

3.23

11 (45304861–45,304,888)

−0.418

6.01E-08

Distal Intergenic

11 (45312449–45,312,737)

−0.308

1.53E-10

Promoter (2-3 kb)

11 (45313729–45,313,893)

−0.34

4.93E-09

Promoter (1-2 kb)

11 (45317381–45,317,584)

0.399

4.47E-20

Intron

11 (45327134–45,327,228)

−0.519

6.13E-12

Intron

11 (45328297–45,328,427)

−0.372

1.50E-07

Intron

11 (45345547–45,345,760)

−0.368

9.78E-08

Intron

11 (45360455–45,360,557)

0.371

2.30E-07

Intron

11 (45379302–45,379,326)

−0.374

1.46E-08

Intron

11 (45380382–45,380,415)

−0.413

8.46E-09

Intron

11 (45390429–45,390,641)

0.368

4.67E-06

Intron

11 (45398919–45,399,057)

0.371

2.28E-08

Intron

11 (45434897–45,434,935)

0.522

4.15E-08

Distal Intergenic

DIAPH1

1.79 ± 0.12

9.73 ± 1.47

3.08

5 (50071804–50,071,997)

−0.382

2.45E-16

Intron

5 (50074050–50,074,580)

− 0.343

3.12E-15

Intron

5 (50078005–50,078,016)

−0.515

9.21E-17

Intron

5 (50093277–50,093,488)

−0.51

4.68E-11

Promoter (1-2 kb)

NR4A1

1.9 ± 0.64

46.14 ± 5.86

5.20

3 (134110748–134,110,763)

−0.462

4.49E-10

Distal Intergenic

3 (134112701–134,112,875)

−0.4

1.53E-08

Intron

3 (134118207–134,118,238)

−0.474

3.23E-06

Promoter (1-2 kb)

DLK1

123.79 ± 16.79

1.59 ± 0.18

−5.62

18 (64227388–64,227,489)

0.315

4.53E-06

Distal Intergenic

18 (64229987–64,230,060)

0.566

1.12E-11

Distal Intergenic

18 (64285447–64,285,772)

0.315

2.15E-09

Distal Intergenic

18 (64297875–64,297,887)

0.509

2.27E-07

Distal Intergenic

18 (64322164–64,322,397)

0.303

7.14E-08

Distal Intergenic

18 (64325751–64,325,850)

0.31

2.10E-05

Promoter (2-3 kb)

18 (64332000–64,332,064)

0.361

5.28E-05

Exon

18 (64374254–64,374,306)

0.372

2.43E-05

Distal Intergenic

18 (64374640–64,374,824)

0.567

2.60E-33

Distal Intergenic

18 (64379476–64,379,559)

0.418

1.43E-05

Distal Intergenic

COL1A2

1509.82 ± 168.72

166.04 ± 40.84

−2.53

4 (11479735–11,479,933)

0.316

1.92E-05

Distal Intergenic

4 (11513253–11,513,266)

−0.37

2.60E-06

Distal Intergenic

4 (11551771–11,551,783)

0.433

2.40E-08

Distal Intergenic

4 (11553777–11,553,809)

0.334

7.76E-06

Distal Intergenic

4 (11712184–11,712,329)

0.309

5.19E-12

Distal Intergenic