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Fig. 1 | BMC Genomics

Fig. 1

From: ICGEC: a comparative method for measuring epigenetic conservation of genes via the integrated signal from multiple histone modifications between cell types

Fig. 1

Relationship between gene expression levels and associated epigenetic levels of different histone modifications. Boxplots show the distribution patterns of the epigenetic levels of 16 investigated marks for genes in MSC with low expression (RPKM≤1), intermediate expression (1 < RPKM≤10) and high expression (RPKM > 10)). The levels of histone modifications are from the entire gene locus (Promoter+Body regions). Statistical analysis indicates that the genes with high expression have higher epigenetic levels than the genes with low expression for all except for two repressive marks H3K27me3 and H3K9me3 that display an opposite trend (one-sided Wilcox rank-sum test, P-value < 0.05)

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BMC Genomics

ISSN: 1471-2164

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