Fig. 6

Characterization of DDSGs and DDUGs. a Heatmap showing the gene scores of DDSGs. Genes are organized by the cell line in which the epigenetic conservation is lowest across the four developmental directions. Known mark genes defined by expression pattern that happen to be DDSGs are shown on the right. b Bubble chart displaying the overrepresented GO terms for DDSGs. c Heatmap showing the gene scores of DDUGs. d Comparison of mark scores for each histone mark across the four differentiation directions. The data are clustered for better representation. The labels on the x-axis in (a-d) represent the specific derived cell line-associated differentiation directions