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Fig. 2 | BMC Genomics

Fig. 2

From: A novel missense mutation in the gene encoding major intrinsic protein (MIP) in a Giant panda with unilateral cataract formation

Fig. 2

Characterization of the mutation in the MIP gene of Jini. (a) Extended structure of MIP, showing the six transmembrane domains (H1–H6), extracellular loops (A/C/E), intracellular loops (B/D), the intracellular N-terminal portion, and the intracellular C-terminal tail, the latter containing the mutation site (red dot). (b) Sequence trace of the 16-bp region spanning the mutation site, comparing the 18 controls (top) and Jini (bottom), revealing the heterozygous mutation (c.686G > A)

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BMC Genomics

ISSN: 1471-2164

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