CEACAM loci in primates. The chromosomal arrangement of CEACAM genes in selected primates is depicted. Arrowheads represent genes with their transcriptional orientation. The PSG genes are shown in red, CEACAM1-related CEACAM genes in yellow, orthologous CEACAM genes in blue, selected flanking genes in black. The PSG clusters are marked with red boxes. The nonsyntenic localization of the PSG cluster in rodents is indicated by a red line at the bottom. The CEACAM gene loci were aligned along the position of CEACAM1 (yellow line), the CEACAM16 loci are connected with a blue line. Names of CEACAM1-like genes with ITIM/ITSM-encoding exons are shown in red and with ITAM and ITAM-like motif-encoding exons in green and blue, respectively. The nucleotide numbering of the chromosomes starts at the telomere of the short arms which point to the right. The chromosomal or scaffold location, databases and their versions used are indicated below the species name. The place corresponding to the location of the PSG-like gene (not found in marmoset) in capucin (Cca) and Bolivian squirrel monkeys (Sbo) is indicated by a red arrow. Of note: The primate genomes (except the human genome) are not completely refined yet. Therefore, not all CEACAM genes identified in WGS databases have been found in the published assembled genomes. C, CEACAM; Chr, chromosome; CP, CEACAM pseudogene; C3L(P), C4L(P), C5L, C6L(P), CEACAM3, 4, 5, 6-like (pseudo)gene; Mbp, million base pairs; P, pregnancy-specific glycoprotein (PSG) genes; PL, PSG-like; P10P, PSG10 pseudogene; PP2, PP3, PSG pseudogene 2, 3.