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Fig. 3 | BMC Genomics

Fig. 3

From: Transcriptome profiling of Lymnaea stagnalis (Gastropoda) for ecoimmunological research

Fig. 3

Expression levels of selected transcripts that represent different components of the immune system. Heatmap shows transcripts that deviated in their transcription between certain experimental treatments and their specific controls and components of the immune system in which individuals expressed distinct transcripts. Examined immunological pathways/mechanisms included non-self recognition, Toll-like receptor (TLR) signaling pathway, cytokines, antibacterial defence, production of reactive oxygen species (ROS), and phenoloxidase (PO)/melanisation-type reaction. Transcripts within each pathway/mechanism are clustered according to their similarity. Heatmap shows the variation for each factor among all experimental snails (each column represents one snail) using its dynamic range in units of transcripts per million (TPM). Red (injections with bacteria), blue (injections with snail/trematode tissue extracts), purple (injections with bacteria and snail/trematode tissue extracts) and black (exposures to environmental change) rectangles (dashed line), arrows and numbers refer to the specific results mentioned in the text

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