Fig. 2

Borrelia burgdorferi (Bb) infection modifies protein content on composition of Ixodes scapularis nymphs. Cumulative normalized spectral abundance factor (NSAF) value, the index for relative protein abundance for all proteins in saliva of uninfected and Bb infected nymph ticks was normalized using the z-score statistics and then used to generate heat maps using heatmap2 function in gplots library using R as described in materials and methods. The red to blue transition denotes high to low abundance levels shown in the Z-score range key. The reader is advised that the raw NSAF values that were used to generate the heatmap are provided in S1 Table