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Fig. 6 | BMC Genomics

Fig. 6

From: Transcriptomics analysis of Toxoplasma gondii-infected mouse macrophages reveals coding and noncoding signatures in the presence and absence of MyD88

Fig. 6

A minimal number of protein-coding genes were differentially expressed between wild type and MyD88 KO BMDM. Macrophages from wild type and MyD88 KO mice were infected with either the RH or PTG strain, and 6 h later RNA was isolated for sequencing. Differentially expressed mouse protein-coding transcripts between wild type and MyD88 KO BMDM were identified based on statistical significance (PPDE greater than 0.95) and a fold change of greater or less than 2. a Total number of protein-coding transcripts of higher or lower abundance between wild type and MyD88 KO mice for uninfected, RH-infected, and PTG-infected samples. b Venn diagrams of the gene expression differences between wild type and MyD88 KO mice showing shared expression changes for uninfected, RH-infected, and PTG-infected samples. c Venn diagrams revealing similarities between wild type and MyD88 KO gene expression changes for RH vs. uninfected, PTG vs. uninfected, and PTG vs. RH. d List of all differentially expressed protein-coding transcripts between wild type and MyD88 KO mice. Coloring indicates those transcripts shared between comparisons

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