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Fig. 7 | BMC Genomics

Fig. 7

From: Transcriptomics analysis of Toxoplasma gondii-infected mouse macrophages reveals coding and noncoding signatures in the presence and absence of MyD88

Fig. 7

Only a few non-coding genes were differentially expressed between wild type and MyD88 KO BMDM. Cells from wild type and MyD88 KO mice were infected with Toxoplasma tachyzoites, and RNA was isolated for sequencing 6 h later. Differentially expressed mouse non-coding transcripts between wild type and MyD88 KO BMDM were identified based on statistical significance (PPDE greater than 0.95) and a fold change of greater or less than 2. a Total number of non-coding transcripts of higher or lower abundance between wild type and MyD88 KO macrophages for uninfected, RH-infected, and PTG-infected samples. b Venn diagrams of the non-coding gene expression differences between wild type and MyD88 KO cells revealing shared expression changes for uninfected, RH-infected, and PTG-infected samples. c Venn diagrams indicating similarities between wild type and MyD88 KO non-coding gene expression changes for RH vs. uninfected, PTG vs. uninfected, and PTG vs. RH. d List of all differentially expressed non-coding transcripts between wild type and MyD88 KO BMDM. Colored transcripts indicate those shared by different comparisons

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