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Fig. 1 | BMC Genomics

Fig. 1

From: The eukaryotic MEP-pathway genes are evolutionarily conserved and originated from Chlaymidia and cyanobacteria

Fig. 1

Distribution of isoprenoid biosynthesis-pathways across lineages. a Distribution of mevalonate (MVA) and/or methylerythritol dicyclophosphate (MEP) pathways, the two isoprenoid biosynthesis-pathways across linages of eukaryotes, Achaea, and eubacteria. The rectangular boxes display the presence (filled) or absence of (blank) MVA- or MEP-pathway in each of the lineages. b Schematic presentation of the seven enzymes of the MEP-pathway producing the two universal five-carbon precursors, isopentenyl diphosphate (IPP) and its isomer dimethylallyl diphosphate (DMAPP). DXS: 1-deoxy-D-xylulose-5-phosphate synthase. DXR: 1-deoxy-D-xylulose 5-phosphate reductoisomerase. CMS: 4-Diphosphocytidyl-2C-methyl-D-erythritol synthase. CMK: 4-(cytidine 5′-diphospho)-2-C-methyl-D-erythritol kinase activity. MDS: 2C-methyl-d-erythritol 2, 4-cyclodiphosphate synthase. HDS: 4-hydroxy-3-methylbut-2-enyl diphosphate synthase. HDR: and 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase

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BMC Genomics

ISSN: 1471-2164

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