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Table 2 Top 20 DE genes from a multi-species transcriptome meta-analysis. RNA-seq data from five different cell types from four different vertebrate species after retinoic acid exposure were subjected to differential expression analysis and used as input for a meta-analysis

From: Multi-species transcriptome meta-analysis of the response to retinoic acid in vertebrates and comparative analysis of the effects of retinol and retinoic acid on gene expression in LMH cells

Symbol LFC p-value
SKAP1 1.999 7.44 × 10−6
SLCO2B1 1.671 7.51 × 10− 6
GDNF 2.144 7.52 × 10− 5
SMAD3 1.111 4.93 × 10− 4
GP5 3.264 6.99 × 10− 4
HIVEP2 4.400 7.56 × 10− 4
HIC1 5.389 1.49 × 10− 3
CYP26A1 3.601 1.67 × 10− 3
MIR6566 1.472 2.34 × 10− 3
ETS2 1.700 2.75 × 10− 3
TDRD9 1.487 3.16 × 10− 3
ERMN 3.539 3.84 × 10− 3
COL24A1 2.356 4.13 × 10− 3
TTYH3 1.072 4.25 × 10− 3
NOTCH2 1.276 4.40 × 10− 3
GPR61 1.196 5.13 × 10− 3
ADAM28 1.826 5.30 × 10− 3
KCNIP1 5.450 5.33 × 10− 3
NOXA1 1.309 5.65 × 10− 3
STXBP4 2.781 6.31 × 10− 3
  1. ADAM28 Disintegrin and metalloproteinase domain-containing protein 28, COL24A1 Collagen alpha-1(XXIV) chain, CYP26A1 Cytochrome P450 26A1, ERMN Ermin, ETS2 Protein C-ets-2, GDNF Glial cell line-derived neurotrophic factor, GP5 Platelet glycoprotein V, GPR61 G-protein coupled receptor 61, HIC1 Hypermethylated in cancer 1 protein, HIVEP2 Transcription factor HIVEP2, KCNIP1 Kv channel-interacting protein 1, MIR6566 MicroRNA 6566, NOTCH2 Neurogenic locus notch homolog protein 2, NOXA1 NADPH oxidase activator 1, SKAP1 Src kinase-associated phosphoprotein 1, SLCO2B1 Solute carrier organic anion transporter family member 2B1, SMAD3 Mothers against decapentaplegic homolog 3, STXBP4 Syntaxin-binding protein 4, TDRD9 ATP-dependent RNA helicase TDRD9, TTYH3 Protein tweety homolog 3