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Table 2 Top 20 DE genes from a multi-species transcriptome meta-analysis. RNA-seq data from five different cell types from four different vertebrate species after retinoic acid exposure were subjected to differential expression analysis and used as input for a meta-analysis

From: Multi-species transcriptome meta-analysis of the response to retinoic acid in vertebrates and comparative analysis of the effects of retinol and retinoic acid on gene expression in LMH cells

Symbol

LFC

p-value

SKAP1

1.999

7.44 × 10−6

SLCO2B1

1.671

7.51 × 10− 6

GDNF

2.144

7.52 × 10− 5

SMAD3

1.111

4.93 × 10− 4

GP5

3.264

6.99 × 10− 4

HIVEP2

4.400

7.56 × 10− 4

HIC1

5.389

1.49 × 10− 3

CYP26A1

3.601

1.67 × 10− 3

MIR6566

1.472

2.34 × 10− 3

ETS2

1.700

2.75 × 10− 3

TDRD9

1.487

3.16 × 10− 3

ERMN

3.539

3.84 × 10− 3

COL24A1

2.356

4.13 × 10− 3

TTYH3

1.072

4.25 × 10− 3

NOTCH2

1.276

4.40 × 10− 3

GPR61

1.196

5.13 × 10− 3

ADAM28

1.826

5.30 × 10− 3

KCNIP1

5.450

5.33 × 10− 3

NOXA1

1.309

5.65 × 10− 3

STXBP4

2.781

6.31 × 10− 3

  1. ADAM28 Disintegrin and metalloproteinase domain-containing protein 28, COL24A1 Collagen alpha-1(XXIV) chain, CYP26A1 Cytochrome P450 26A1, ERMN Ermin, ETS2 Protein C-ets-2, GDNF Glial cell line-derived neurotrophic factor, GP5 Platelet glycoprotein V, GPR61 G-protein coupled receptor 61, HIC1 Hypermethylated in cancer 1 protein, HIVEP2 Transcription factor HIVEP2, KCNIP1 Kv channel-interacting protein 1, MIR6566 MicroRNA 6566, NOTCH2 Neurogenic locus notch homolog protein 2, NOXA1 NADPH oxidase activator 1, SKAP1 Src kinase-associated phosphoprotein 1, SLCO2B1 Solute carrier organic anion transporter family member 2B1, SMAD3 Mothers against decapentaplegic homolog 3, STXBP4 Syntaxin-binding protein 4, TDRD9 ATP-dependent RNA helicase TDRD9, TTYH3 Protein tweety homolog 3