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Table 3 Sex specific DEGs in adrenal

From: Strain-based and sex-biased differences in adrenal and pancreatic gene expression between KK/HlJ and C57BL/6 J mice

Gene symbol

Gene name

Accession number

Average fold change

Upregulated in male mice compared to female

 DDX3Y

Dead (Asp-Glu-Ala-Asp) Box Polypeptide 3, Y-Linked

NM_012008

18.36

 Mup20

Major Urinary Protein 20

NM_001012323

12.92

 Uty

Ubiquitously Transcribed Tetratricopeptide Repeat Gene, Y Chromosome

NM_009484

12.27

 Eif2s3y

Eukaryotic Translation Initiation Factor 2, Subunit 3, Structural gene Y-linked

NM_012011

9.60

 Acan

Aggrecan

NM_007424

8.52

 KDM5D

Lysine (K)-Specific Demethylase 5D

NM_011419

8.24

 LY6D

Lymphocyte Antigen 6 Complex, Locus D

NM_010742

5.42

 Astx4d

Amplified Spermatogenic Transcripts X Encoded 4D

ENSMUST00000123136

5.17

 CXCR4

Chemokine (C-X-C Motif) Receptor 4

NM_009911

4.96

 Astx1c

Amplified Spermatogenic Transcripts X Encoded 1C

ENSMUST00000177724

4.92

 HSD3B6

Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- And Steroid Delta Isomerase 6

NM_013821

4.87

 APLN

Apelin

NM_013912

4.39

 Astx3

Amplified Spermatogenic Transcripts X Encoded 3

ENSMUST00000123508

4.35

 MYOT

Myotilin

NM_001033621

4.04

 MMP12

Matrix metallopeptidase 12

NM_008605

3.75

 Srsy

Serine-Rich, Secreted, Y-Linked

XR_106321

3.32

 KCNK1

Potassium Channel, Subfamily K, Member 1

NM_008430

3.28

 C7

Complement Component 7

NM_001243837

3.22

 Astx

Amplified Spermatogenic Transcripts X Encoded

XR_878232

3.21

 Ssty2

Spermiogenesis Specific Transcript on The Y2

NM_023546

3.20

 SRD5A2

Steroid 5 Alpha-Reductase 2

NM_053188

3.17

 ETNK2

Ethanolamine Kinase 2

NM_175443

2.93

 HSPB1

Heat Shock Protein 1

NM_013560

2.90

 Ppbp

Pro-Platelet Basic Protein

NM_023785

2.67

 KCNK9

Potassium Channel, Subfamily K, Member 9

NM_001033876

2.64

 SEMA5B

Sema Domain, Seven Thrombospondin Repeats (Type 1 And Type 1-Like)

NM_013661

2.62

 VSNL1

Visinin-Like 1

NM_012038

2.62

 FGF11

Fibroblast Growth Factor 11

NM_001291104

2.60

 IGFBP5

Insulin-Like Growth Factor Binding Protein 5

NM_010518

2.57

 Nnat

Neuronatin

NM_001291128

2.14

 Gm29413

Unknown

ENSMUST00000186019

6.50

 Gm21248

Unknown

XM_003689090

5.41

 Gm20867

Unknown

NM_001160142

5.36

 Gm20816

Unknown

NM_001160144

5.30

 Gm20738

Unknown

NM_207162

5.12

 Gm20823

Unknown

NM_001160143

5.03

 Gm21242

Unknown

XM_003689089

4.75

Downregulated in male mice compared to female

 Akr1c18

Aldo-Keto Reductase Family 1, Member C18

NM_134066

−100.69

 XIST

Inactive X Specific Transcripts

NR_001463

−93.61

 AKR1D1

Aldo-Keto Reductase Family 1, Member D1

NM_145364

−70.31

 FETUB

Fetuin Beta

NM_001083904

−14.88

 CD1D1

CD1d1 Antigen

NM_007639

−10.79

 C3

Complement Component 3

NM_009778

−9.92

 SERPINB1

Serine (or Cysteine) Peptidase Inhibitor, Clade B, Member 1A

NM_025429

−8.71

 Hamp2

Hepcidin Antimicrobial Peptide 2

NM_183257

−8.69

 NREP

Neuronal Regeneration Related Protein

NM_001109988

−8.28

 A2M

Alpha-2-Macroglobulin

NM_175628

−8.22

 GPAM

Glycerol-3-Phosphate Acyltransferase, Mitochondrial

NM_008149

−6.20

 Masp1

Mannan-Binding Lectin Serine Peptidase 1

NM_008555

−6.04

 PRR16

Proline Rich 16

NM_001081224

−5.73

 Vnn3

Vanin 3

NM_011979

−5.39

 APPL2

Adaptor Protein, Phosphotyrosine Interaction, Ph Domain and Leucine

NM_145220

−5.14

 FMO1

Flavin Containing Monooxygenase 1

NM_010231

−5.02

 MGST2

Microsomal Glutathione S-Transferase 2

NM_001310482

−4.95

 ELFN1

Leucine Rich Repeat and Fibronectin Type III, Extracellular 1

NM_175522

−4.88

 ADH7

Alcohol Dehydrogenase 7 (Class IV), Mu or Sigma Polypeptide

NM_009626

−4.57

 MAPK13

Mitogen-Activated Protein Kinase 13

NM_011950

−4.22

 TCF24

Transcription Factor 24

NM_001285425

− 4.03

 LRRK2

Leucine-Rich Repeat Kinase 2

NM_025730

− 4.02

 MGST1

Microsomal Glutathione S-Transferase 1

NM_019946

−3.87

 ST3GAL1

St3 Beta-Galactoside Alpha-2,3-Sialyltransferase 1

NM_009177

−3.85

 CHKA

Choline Kinase Alpha

NM_001271496

−3.82

 RFK

Riboflavin Kinase

NM_019437

−3.70

 NR0B1

Nuclear Receptor Subfamily 0, Group B, Member 1

NM_007430

−3.66

 THRB

Thyroid Hormone Receptor Beta

NM_001113417

−3.58

 SPRY3

Sprouty Homolog 3 (Drosophila)

NM_001030293

−3.56

 FAT4

Fat Tumor Suppressor Homolog 4 (Drosophila)

NM_183221

−3.47

 Gm15883

Unknown

ENSMUST00000153562

−3.18

 Gm24277

Unknown

ENSMUST00000158661

−3.08

 Gm22866

Unknown

ENSMUST00000083947

−2.82

 Gm20482

Unknown

XR_391144

−2.77

 Gm19689

Unknown

NR_045094

−2.25

 Gm15992

Unknown

ENSMUST00000130307

−2.25

Gm15895

Unknown

XR_388023

−2.19

  1. DEG Differentially Expressed Gene