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Table 4 Common strain specific DEGs in adrenal and pancreas

From: Strain-based and sex-biased differences in adrenal and pancreatic gene expression between KK/HlJ and C57BL/6 J mice

Gene symbol

Gene name

Accession number

Average fold change

Upregulated genes in KK/HlJ mice compared to C57BL/6 J mice

 Mela

Melanoma Antigen, Gal-Pol Polyprotein

BC113756

−32.57

 Snord53

Small Nucleolar RNA, C/D Box 53

NR_028551

−8.01

 GDPD3

Glycerophosphodiester Phosphodiesterase Domain Containing 3

NM_024228

−5.97

 Abhd1

Abhydrolase Domain Containing 1

NM_021304

−5.00

 RETSAT

Retinol Saturase

NM_026159

−4.85

 SLC37A1

Solute Carrier Family 37 (Glycerol-3-Phosphate Transporter)

NM_001242427

−4.17

 PTPRN

Protein Tyrosine Phosphatase, Receptor Type, N

NM_008985

−3.83

 CHGB

Chromogranin B

NM_007694

−3.60

 LBP

Lipopolysaccharide Binding Protein

NM_008489

−3.13

 PCSK2

Proprotein Convertase Subtilisin/Kexin type 2

NM_008792

−3.12

 MASP2

Mannan-binding Lectin Serine Peptidase 2

NM_001003893

−2.93

 STK32A

Serine/Threonine Kinase 32A

NM_178749

−2.69

 TPM3

Tropomyosin 3, gamma

BC092045

−2.67

 Nnt

Nicotinamide Nucleotide Transhydrogenase

NM_001308506

−2.33

 DISP2

Dispatched Homolog 2 (Drosophila)

NM_170593

−2.32

 UNC80

Unc-80 Homolog

NM_175510

−2.31

 RPL3

Ribosomal Protein L3

BC009655

−2.29

 SCG5

Secretogranin V

NM_009162

−2.28

 GRIA2

Glutamate Receptor, Ionotropic, AMPA2 (alpha 2)

NM_001039195

−2.06

 RIMBP2

RIMS Binding Protein 2

NM_001081388

−2.00

 ST18

Suppression of Tumorigenicity 18

NM_001244692

−1.89

 PCSK1N

Proprotein Convertase Subtilisin/Kexin Type 1 Inhibitor

NM_013892

−1.80

 APLP1

Amyloid Beta (A4) Precursor-Like Protein 1

NM_007467

−1.79

 RUNDC3A

RUN Domain Containing 3A

NM_001252347

−1.64

 LRP11

Low Density Lipoprotein Receptor-Related Protein 11

NM_172784

−1.55

 BC023719

Unknown

BC023719

−27.64

 BC018473

Unknown

BC018473

−15.31

 LOC100861738

Unknown

LOC100861738

−4.22

 1700020D05Rik

Unknown

1700020D05Rik

−3.67

 Gm3264

Unknown

Gm3264

−2.85

 Gm9855

Unknown

Gm9855

−2.79

 Gm3383

Unknown

NM_001291093

−2.94

Upregulated genes in C57BL/6 J mice compared to KK/HlJ mice

 Igkv10–96

Immunoglobulin Kappa Variable 10–96

OTTMUST00000132012

136.82

 H2-T22

Histocompatibility 2, T Region Locus 22

NM_010397

17.34

 HIST1H4K

Histone Cluster 1, H4k

NM_178211

9.06

 GABRA3

Gamma-Aminobutyric Acid (GABA) A Receptor, Subunit Alpha 3

NM_008067

8.32

 RAB6B

RAB6B, Member RAS Oncogene Family

NM_173781

8.13

 HIST1H2BC

Histone Cluster 1, H2bc

NM_023422

5.59

 CFD

Adipsin Complement Factor D

NM_001291915

5.32

 CYP2E1

Cytochrome P450, Family 2, Subfamily E, Polypeptide 1

NM_021282

4.34

 LY96

Lymphocyte Antigen 96

NM_001159711

3.39

 Trac

T-cell Receptor Alpha Constant

OTTMUST00000134701

3.37

 Tcrg-C2

T-cell Receptor Gamma, Constant 2

OTTMUST00000134792

3.34

 Mnda

Myeloid Cell Nuclear Differentiation Antigen

NM_001033450

3.26

 Ifna4

Interferon Alpha 4

NM_010504

2.95

 PTTG1

Pituitary Tumor-Transforming Gene 1

NM_001131054

2.88

 IRGM2

Immunity-Related GTPase Family M Member 2

NM_019440

2.76

 LAPTM5

Lysosomal-Associated Protein Transmembrane 5

NM_010686

2.73

 HIST1H4M

Histone Cluster 1, H4m

NM_001195421

2.70

 Adig

Adipogenin

NM_145635

2.65

 ITGA1

Integrin Alpha 1

NM_001033228

2.62

 MID1

Midline 1

NM_001290504

2.60

 RTP4

Receptor Transporter Protein 4

NM_023386

2.43

 NFU1

NFU1 Iron-Sulfur Cluster Scaffold Homolog

NM_001170591

2.14

 GPX8

Glutathione Peroxidase 8 (Putative)

NM_027127

2.13

 CTSH

Cathepsin H

NM_001312649

2.13

 DECR2

2–4-Dienoyl-Coenzyme A Reductase 2, Peroxisomal

NM_011933

2.12

 IFIH1

Interferon Induced with Helicase C Domain 1

NM_001164477

1.99

 EAPP

E2F-Associated Phosphoprotein

NM_025456

1.85

 DENND2D

DENN/MADD Domain Containing 2D

NM_001093754

1.79

 TSPAN6

Tetraspanin 6

NM_019656

1.77

 SCPEP1

Serine Carboxypeptidase 1

NM_029023

1.62

 9930111J21Rik2

Unknown

9930111J21Rik2

10.41

 Gm38463

Unknown

Gm38463

5.93

 4930481A15Rik

Unknown

4930481A15Rik

4.29

 2610507I01Rik

Unknown

2610507I01Rik

4.29

 5830417I10Rik

Unknown

5830417I10Rik

4.25

 Gm20236

Unknown

Gm20236

3.68

  1. DEG Differentially Expressed Gene