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Table 2 Comparing p-values for EcoCyc CYSTSYN-PWY and KEGG map00270

From: Pathway size matters: the influence of pathway granularity on over-representation (enrichment analysis) statistics

Count of Significantly Expressed Genes

EcoCyc p-value

Corrected for Multiple Comparisons

Native KEGG p-value

Corrected for Multiple Comparisons

3

4.6×10−9

1.6×10−6

7.5×10−6

8.9×10−4

2

5.0×10−6

1.8×10−3

3.9×10−4

4.7×10−2

1

2.7×10−3

9.7×10−1

2.0×10−2

1.0

  1. Each row starts with the number of significantly expressed genes in a data set. Corrected p-values to the right of each p-value column use Bonferroni as a “worst case” correction as discussed in the text