Skip to main content

Table 3 Comparing p-values for EcoCyc ARGSYN-PWY and KEGG map00220

From: Pathway size matters: the influence of pathway granularity on over-representation (enrichment analysis) statistics

Count of Significantly Expressed Genes EcoCyc p-value Corrected for Multiple Comparisons Native KEGG p-value Corrected for Multiple Comparisons
12 1.7×10−28 6.0×10−26 1.8×10−26 2.1×10−24
11 1.8×10−25 6.5×10−23 4.2×10−24 5.0×10−22
10 1.0×10−22 3.5×10−20 8.8×10−22 1.0×10−19
9 3.6×10−20 1.3×10−17 1.6×10−19 1.9×10−17
8 9.8×10−18 3.5×10−15 2.7×10−17 3.3×10−15
7 2.1×10−15 7.6×10−13 4.2×10−15 5.0×10−13
6 3.9×10−13 1.4×10−10 5.9×10−13 7.0×10−11
5 6.1×10−11 2.1×10−8 7.6×10−11 9.0×10−9
4 8.3×10−9 2.9×10−6 9.1×10−9 1.1×10−6
3 1.0×10−6 3.6×10−4 1.0×10−6 1.2×10−4
2 1.1×10−4 3.9×10−2 1.1×10−4 1.3×10−2
1 1.1×10−2 1.0 1.1×10−2 1.0
  1. Corrected p-values to the right of each p-value column use Bonferroni as a “worst case” correction as discussed in the text