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Table 4 Comparing p-values for EcoCyc PWY0-901 and KEGG map00450

From: Pathway size matters: the influence of pathway granularity on over-representation (enrichment analysis) statistics

Count of Significantly Expressed Genes

EcoCyc p-value

Corrected for Multiple Comparisons

Native KEGG p-value

Corrected for Multiple Comparisons

4

1.7×10−11

5.9×10−9

7.2×10−9

8.5×10−7

3

1.8×10−8

6.5×10−6

8.5×10−7

1.0×10−4

2

1.0×10−5

3.5×10−3

9.6×10−5

1.1×10−2

1

3.6×10−3

1.0

1.0×10−2

1.0

  1. Corrected p-values to the right of each p-value column use Bonferroni as a “worst case” correction as discussed in the text