Fig. 1

The assessment of lifestyle modification mice model establishment. Body weight of different lifestyle groups at the beginning and the end of the treatment (a). Visceral fat mass (b), total fat mass (c) and total lean mass (e) were detected by DEXA at the beginning and the end of the treatment. Body fat percentage (d) and lean mass percentage (f) were calculated. The frozen-fixed mice skeletal muscle was cut into 20 μm sections and stained by Oil Red O (g). Black arrows indicated the ectopic lipid accumulations. Data are presented as Means ± SE (n = 7 in each group). AL: ad libitum, CR: caloric restriction, EX: exercise, HF: high-fat diet. (**: p < 0.01 vs AL)