Comparison | PPA (%) | NPA (%) | No Calls (Average) |
|---|
Accuracy, .4x vs PMRA | 98.22% | 99.82% | 2535 |
Accuracy, .6x vs PMRA | 98.76% | 99.85% | 1848 |
Accuracy, .8x vs PMRA | 99.01% | 99.86% | 1508 |
Accuracy, 1x vs PMRA | 99.19% | 99.88% | 1251 |
- In all cases the genotyping array was treated as ‘Truth’. Positive % Agreement (PPA)– The percent of non-reference calls in the Truth dataset detected by Test, ignoring no calls in Test. (True Positives / True Positives + False Negatives). Negative % Agreement (NPA) – The percent of reference calls in the Truth dataset detected by Test, ignoring no calls in Test. (True Negatives / True Negatives + False Positives). No Calls– Count of No Calls in test that were variant in Truth. No calls are averaged across all 79 individuals. The total number of overlapping variants between the PMRA and the imputed sequence data is ~ 423 k
