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Fig. 3 | BMC Genomics

Fig. 3

From: Mitochondrial genotype alters the impact of rapamycin on the transcriptional response to nutrients in Drosophila

Fig. 3

Mitonuclear genotype alters the transcriptional response of rapamycin sensitive OXPHOS genes. a A heatmap of the genes found to have significantly different response patterns to refeeding with rapamycin treatment between the OreR;OreR (OO) and sm21;OreR (SO) mtDNA genotypes. On the x-axis, the genes are organized and color coded according to the expression profiles established by MBCluster-seq while on the y-axis samples are separated into the four GxT condition time courses. The mean expression data is normalized by row, with the cell color indicating the z-score for the gene at a specified GxT time point. b-c Normalized expression data for the OXPHOS genes in cluster 1 (b) and cluster 5 (c) plotted as grey lines with the cluster means overlaid in blue for control treated samples and red for rapamycin treated samples

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