Skip to main content
Fig. 5 | BMC Genomics

Fig. 5

From: Mitochondrial genotype alters the impact of rapamycin on the transcriptional response to nutrients in Drosophila

Fig. 5

Developmental stage-specific and tissue-specific expression for genes in different co-expressed clusters. Genes identified as having differential expression between mitonuclear genotype in response to refeeding with rapamycin from the cluster 1 and cluster 5 expression profiles were independently analyzed for enrichment of expression at different developmental stages or in different tissues. a The Drosophila modEncode Developmental Transcriptome Profile data set [40] was used to examine development stage specific gene expression. Expression levels provided by the public data set for genes in cluster 1 (left) and cluster 5 (right) were normalized to the mean level of all genes measured at the specified developmental stage. Displayed are the normalized expression levels observed for male (blue) and female (red) samples at 1, 5 and 30 days post eclosion. b The FlyAtlas2 database [41] was used to examine tissue specific gene expression patterns. Expression levels for the cluster 1 (left) and cluster 5 (right) genes were collected for each of the 15 different tissues measured in the public dataset, and normalized to the level observed in the whole body sample. Displayed are the normalized FPKM expression levels for each of the 15 male tissues investigated

Back to article page