Comparative transcriptome analysis reveals ectopic delta-5 and delta-6 desaturases enhance protective gene expression upon Vibrio vulnificus challenge in Tilapia (Oreochromis niloticus)

Table 6 Gene ontology analysis of wild-type and transgenic tilapia fish expressing delta-6 desaturase plus delta-5 desaturase (D56) infected with V. vulnificus for 6 h

GO number	Gene ontology term	Cluster frequency	Corrected P-value
	Cellular component
GO:0042613	MHC class II protein complex	4/388	0.00111901
GO:0005576	extracellular region	10/388	0.005273844
GO:0000145	exocyst	2/388	0.023258951
	Biological process
GO:0006879	cellular iron ion homeostasis	5/388	7.19886E-06
GO:0019882	antigen processing and presentation	4/388	0.001296795
GO:0006955	immune response	7/388	0.00147042
GO:0005975	carbohydrate metabolic process	5/388	0.006899818
GO:0006629	lipid metabolic process	4/388	0.008996727
GO:0006096	glycolytic process	2/388	0.026732255
	Molecular function
GO:0004252	serine-type endopeptidase activity	12/388	3.58836E-06
GO:0004866	endopeptidase inhibitor activity	5/388	7.56213E-05
GO:0016491	oxidoreductase activity	8/388	0.00035261
GO:0003824	catalytic activity	8/388	0.000514237
GO:0016788	hydrolase activity, acting on ester bonds	3/388	0.000760589
GO:0004181	metallocarboxypeptidase activity	3/388	0.001314446
GO:0004222	metalloendopeptidase activity	5/388	0.005118182
GO:0016746	transferase activity, transferring acyl groups	3/388	0.006176615
GO:0005125	cytokine activity	2/388	0.009116399
GO:0008289	lipid binding	3/388	0.032301052
GO:0005506	iron ion binding	4/388	0.034540735
GO:0005509	calcium ion binding	9/388	0.037632531
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/388	0.040369571
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/388	0.042492616

ISSN: 1471-2164