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Table 7 Gene ontology analysis of wild-type and transgenic tilapia fish expressing delta-6 desaturase plus delta-5 desaturase (D56) infected with V. vulnificus for 24 h

From: Comparative transcriptome analysis reveals ectopic delta-5 and delta-6 desaturases enhance protective gene expression upon Vibrio vulnificus challenge in Tilapia (Oreochromis niloticus)

 

Gene ontology term

Cluster frequency

Corrected P-value

 

Cellular component

  

GO:0005576

extracellular region

20/614

3.58031E-06

GO:0005737

cytoplasm

12/614

4.79812E-05

GO:0042613

MHC class II protein complex

4/614

0.005816676

GO:0005694

chromosome

2/614

0.016811817

GO:0005667

transcription factor complex

2/614

0.027216225

GO:0005923

bicellular tight junction

4/614

0.038570306

 

Biological process

  

GO:0006096

glycolytic process

7/614

1.13304E-07

GO:0006955

immune response

14/614

4.69497E-07

GO:0006879

cellular iron ion homeostasis

6/614

3.8588E-06

GO:0019882

antigen processing and presentation

4/614

0.006685535

GO:0007160

cell-matrix adhesion

3/614

0.007455887

GO:0008610

lipid biosynthetic process

2/614

0.01454755

GO:0042742

defense response to bacterium

2/614

0.01454755

GO:0043066

negative regulation of apoptotic process

2/614

0.016811817

GO:0009116

nucleoside metabolic process

2/614

0.024421755

GO:0006954

inflammatory response

2/614

0.033166717

 

Molecular function

  

GO:0005506

iron ion binding

27/614

3.83798E-23

GO:0020037

heme binding

26/614

1.05274E-19

GO:0016705

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

22/614

2.62412E-19

GO:0016491

oxidoreductase activity

20/614

5.06286E-12

GO:0003824

catalytic activity

11/614

0.000162737

GO:0004674

protein serine/threonine kinase activity

8/614

0.000452088

GO:0004866

endopeptidase inhibitor activity

5/614

0.000626808

GO:0008009

chemokine activity

6/614

0.000757102

GO:0016702

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

4/614

0.000867978

GO:0005125

cytokine activity

3/614

0.001448524

GO:0042626

ATPase activity, coupled to transmembrane movement of substances

4/614

0.00715045

GO:0008374

O-acyltransferase activity

2/614

0.012426999

GO:0016887

ATPase activity

5/614

0.013302119

GO:0016746

transferase activity, transferring acyl groups

3/614

0.021148212

GO:0016773

phosphotransferase activity, alcohol group as acceptor

2/614

0.021753335

GO:0016758

transferase activity, transferring hexosyl groups

3/614

0.025460073

GO:0003779

actin binding

5/614

0.029257274

GO:0004222

metalloendopeptidase activity

5/614

0.03112367

GO:0019904

protein domain specific binding

2/614

0.036314673