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Table 4 Biological significance of gene set that aid in prediction of BRCA survival and drug response

From: Deep learning assisted multi-omics integration for survival and drug-response prediction in breast cancer

GENE NAME Reported Biomarker function
EFHD1 EF-Hand Domain Family Member D1 Part of digital RNA resistance signature to predict response to breast cancer therapy [31]
CDH1 Cadherin 1 CDH1 structural alterations as novel prognostic biomarker in gastric cancer patients [32]
CDH1 gene as a prognostic biomarker in hepatocellular carcinoma [33]
PIK3CA Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha PIK3CA is a predictive biomarker for use of alpelisib and fulvestrant in BRCA patients [34]
TP53   mutant p53 as a possible therapeutic target and biomarker for breast cancer [35]