Genotype-expression interactions for BDNF across human brain regions

BMC Genomics

Table 3 Association of BDNF expression with demographic factors

Region	Demographic		n	Median_IQR	p-value
Cerebellum	Sex	Female	48 (27.9%)	30 (13.75 ~ 45.25)	0.97
		Male	124 (72.1%)	30.5 (9.75 ~ 50.25)
	Race	Black	17 (9.9%)	18 (13 ~ 33)	0.13
		White	154 (89.5%)	32 (12.25 ~ 50.75)
	Age		172	−0.03	0.70
	BMI		172	−0.0063	0.93
Cortex	Sex	Female	49 (33.1%)	27 (14 ~ 39)	0.18
		Male	99 (66.9%)	33 (17.5 ~ 46)
	Race	Black	17 (11.5%)	22 (4 ~ 38)	0.08
		White	130 (87.8%)	31.5 (18.25 ~ 45)
	Age		148	−0.0238	0.77
	BMI		148	-9e-04	0.99
Nucleus accumbens	Sex	Female	42 (28.8%)	25.5 (12.25 ~ 42.75)	0.90
		Male	104 (71.2%)	28 (15 ~ 41.25)
	Race	Black	13 (9%)	20 (3 ~ 35)	0.14
		White	131 (90.3%)	28 (15 ~ 43)
	Age		146	0.0486	0.56
	BMI		146	0.0778	0.35
Caudate	Sex	Female	38 (26.6%)	33 (18.25 ~ 55)	0.14
		Male	105 (73.4%)	28 (14 ~ 40)
	Race	Black	14 (9.9%)	15.5 (2.25 ~ 26.5)	0.01
		White	127 (89.4%)	33 (17 ~ 46)
	Age		143	0.031	0.71
	BMI		143	0.0031	0.97
Cerebellar Hemisphere	Sex	Female	37 (27.8%)	44 (16 ~ 70)	0.79
		Male	96 (72.2%)	42 (18.75 ~ 69.5)
	Race	Black	11 (8.3%)	25 (16 ~ 40)	0.09
		White	121 (91%)	45 (19 ~ 72)
	Age		133	−0.0192	0.83
	BMI		133	0.1449	0.10

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