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Table 2 Blood plasma biomarkers at d 2 of age in Holstein calves (n = 6/group) born to cows randomly assigned to receive a basal control (CON) diet from − 28 ± 2 d to parturition [1.47 Mcal/kg dry matter (DM) and 15.3% crude protein (CP)] with no added Met or CON plus ethyl cellulose Met (MET, Mepron®, Evonik Nutrition & Care GmbH, Germany)

From: Unique adaptations in neonatal hepatic transcriptome, nutrient signaling, and one-carbon metabolism in response to feeding ethyl cellulose rumen-protected methionine during late-gestation in Holstein cows

Item Maternal diet SEM p-value
CON MET
Glucose (mmol/L) 9.34 8.12 0.35 0.08
Cholesterol (mmol/L) 0.96 0.89 0.07 0.64
Urea (mmol/L) 3.32 3.56 0.24 0.62
Ca (μmol/L) 3.08 2.89 0.07 0.22
P (μmol/L) 2.39 2.27 0.05 0.29
Mg (μmol/L) 1.00 0.96 0.03 0.59
Na (μmol/L) 145.98 147.10 0.87 0.55
K (μmol/L) 4.82 5.44 0.19 0.12
Cl (μmol/L) 99.38 98.92 0.72 0.76
Zn (μmol/L) 10.32 9.78 1.84 0.89
Ceruloplasmin (μmol/L) 0.99 1.01 0.12 0.93
Albumin (g/L) 26.64 27.86 0.47 0.21
AST (U/L) 112.85 128.47 10.49 0.49
GGT (U/L) 1,344.67 1,406.67 145.77 0.84
Bilirubin (μmol/L) 14.73 16.89 1.71 0.55
NEFA (mmol/L) 0.28 0.34 0.05 0.60
Hydroxybutyrate (mmol/L) 0.05 0.09 0.01 0.08
CREA (μmol/L) 107.92 111.67 4.81 0.72
Paraoxonase (U/mL) 12.27 13.02 1.15 0.76
ROM (mg H2O2/100 mL) 13.14 12.86 0.75 0.87
FRAP (μmol/L) 164.50 171.50 8.31 0.70
NOx (μmol/L) 194.00 239.33 22.31 0.33
NO2 (μmol/L) 16.87 10.33 2.56 0.26
NO3 (μmol/L) 156.50 229.00 24.06 0.14
Insulin (μg/L) 1.05 0.70 0.16 0.29