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Table 9 Top 20 downregulated genes among those that were differentially expressed (DEG; FDR ≤0.10) in RNAseq data from liver tissue of 4-d old Holstein calves (n = 6/group) born to cows randomly assigned to receive a basal control (CON) diet from −28 ± 2 d to parturition [1.47 Mcal/kg dry matter (DM) and 15.3% crude protein (CP)] with no added Met or CON plus ethyl cellulose Met (MET, Mepron®, Evonik Nutrition & Care GmbH, Germany)

From: Unique adaptations in neonatal hepatic transcriptome, nutrient signaling, and one-carbon metabolism in response to feeding ethyl cellulose rumen-protected methionine during late-gestation in Holstein cows

Entrez gene id

Gene Symbol

FC

FDR

527,436

MSI1

−4.89

0.07

538,404

MYOM1

−4.08

0.07

521,822

FADS2

−4.02

0.08

526,134

SLC9A2

−3.90

0.09

533,161

KIF2C

−3.78

0.08

518,623

LOC518623

−3.60

0.08

327,679

CCNB1

−3.59

0.07

518,801

CFAP43

−3.40

0.05

528,813

SCNN1D

−3.23

0.08

537,698

GRIK5

−3.22

0.06

281,061

CDK1

−3.15

0.08

281,883

KCNJ2

−3.12

0.07

534,781

PBK

−3.06

0.09

504,746

ECT2

−2.82

0.09

616,767

PRRG4

−2.81

0.10

518,313

KIAA1324L

−2.77

0.08

538,436

CCNE2

−2.72

0.04

785,540

LOC785540

−2.65

0.09

517,383

GPRIN1

−2.42

0.08

615,890

SMG8

−2.40

0.08