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Fig. 2 | BMC Genomics

Fig. 2

From: Strategies for detecting and identifying biological signals amidst the variation commonly found in RNA sequencing data

Fig. 2

Listing of highly correlated genes identified by correlation analysis and their known integrated network affiliations within the immune system. STRING database analysis of the 13 genes found to be highly correlated (r ≥ 0.95725) with the IFIT3 gene. This regulatory cluster is associated with 24 GO pathways that are primarily involved in response to virus (red, GO:0009615), defense response to virus (blue, GO:0051607) and type 1 interferon signaling (green, GO:0060337). Eight of the highlighted genes (red, blue and green) form statistically significant groupings with False Discovery Rates ranging from E− 17 to E− 21 that may collectively integrate the activity of all three pathways

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BMC Genomics

ISSN: 1471-2164

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