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Table 1 Top 15 pTSSs up- or downregulated under hypoxic stress

From: Genome-scale analyses of transcriptional start sites in Mycobacterium marinum under normoxic and hypoxic conditions

Position

Associated gene

FC (H/N)

Product

upregulated

 2,741,615, +

trxB1

30.3

thioredoxin

 5,166,688, +

kgd

23.1

multifunctional oxoglutarate decarboxylase

 5,928,771, +

MMAR_4874

23.1

transcriptional regulator

 19,429, +a

MMAR_p23

23.0

chromosome partitioning protein

 4,722,828, −

porB

22.6

2-oxoacid ferredoxin oxidoreductase subunit beta

 3,034,066, −

MMAR_2491

18.2

zinc ribbon domain-containing protein

 5,952,502, +

MMAR_4896

16.7

hypothetical protein

 2,306,716, +

infB

11.5

translation initiation factor IF-2

 1,233,867, +

MMAR_1007

10.4

transcriptional regulator

 2,424,872, −

sigB

10.4

RNA polymerase sigma factor

 4,231,315, −

MMAR_3428

10.1

hypothetical protein

 1,233,815, −

mmpS5

9.6

membrane protein

 3,478,075, +

MMAR_2872

8.4

multidrug-transport integral membrane protein

 5,945,575, −

purL

7.9

phosphoribosylformylglycinamidine synthase subunit

 6,373,356, +

MMAR_5280

7.3

dihydrodipicolinate reductase

downregulated

 3,623,295, −

MMAR_2999

0.016

OsmC family peroxiredoxin

 2,115,027, +

fadD29

0.054

acyl-CoA synthetase

 5,624,834, +

mntH

0.072

divalent metal cation transporter

 3,801,485, −

MMAR_3116

0.083

undecaprenyl-diphosphate phosphatase

 2,817,295, +

fadD25

0.084

acyl-CoA synthetase

 2,816,979, −

pks5

0.095

probable polyketide synthase

 2,686,224, +

MMAR_2235

0.095

PE-PPE domain-containing protein

 2,838,256, −

MMAR_2352

0.097

GAP family protein

 2,966,269, +

pheT

0.103

phenylalanine-tRNA ligase subunit beta

 1,541,144, +

fadE25

0.117

acyl-CoA dehydrogenase

 5,174,763, −

mdh

0.124

malate dehydrogenase

 572,814, −

MMAR_5555

0.130

hypothetical protein

 3,298,910, +

gcvH

0.132

glycine cleavage system protein H

 4,257,552, +

MMAR_3453

0.136

pyridoxal phosphate-dependent aminotransferase

 1,249,089, +

MMAR_1023

0.137

mycofactocin biosynthesis peptidyl-dipeptidase

  1. a pTSS locates in plasmid (NC_010604.1)