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Fig. 4 | BMC Genomics

Fig. 4

From: Identification of co-expression network correlated with different periods of adipogenic and osteogenic differentiation of BMSCs by weighted gene co-expression network analysis (WGCNA)

Fig. 4

Identification of hub genes. a Volcano plot of Differentially Expression Genes (DEGs) at Ad14d, Ob7d, Ob4h and Ad4h compared to undifferentiated BMSC. Red squares indicate upregulated genes (log2FC > 1), green triangles indicate downregulated genes (log2FC < − 1). Grey dots represent genes that are not statistically different (− 1 < log2FC < 1). b Typical hub cluster of the PPI network in module red, tan, grey60, yellow and green. Red dots represent upregulated genes at corresponding differentiation time point while grey dots represent genes without statistical differenrence. c Venn diagram of overlapped genes between PPI hub cluster genes, DEGs and intra-module hub genes. The overlapped genes are highlighted in fig(A)

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