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Table 1 The 30 most up-regulated DEGs in the magnum of laying compared to non-laying hens

From: RNA sequencing-based analysis of the magnum tissues revealed the novel genes and biological pathways involved in the egg-white formation in the laying hen

Gene Name

Gene Description

Fold Change

AVD

Avidin

250.6824

TMPRSS9

Transmembrane protease, serine 9

33.0611

SLC7A9

Solute carrier family 7 member 9

29.9439

BHLHE23

Basic helix-loop-helix family member e23

17.2940

MMP1

Matrix metallopeptidase 1

16.0790

ACE

Angiotensin converting enzyme

14.8313

SLC26A4

Solute carrier family 26 member 4

9.7876

NIPAL4

NIPA like domain containing 4

8.8105

SLC51B

Solute carrier family 51 beta subunit

8.7190

ATG10

Autophagy related 10

8.6403

LEFTY2

Left-right determination factor 1

8.5433

ACCSL

1-Aminocyclopropane-1-carboxylate synthase homolog (inactive) like

8.4146

GNRHR

Gonadotropin releasing hormone receptor

7.7644

SLC25A4

Solute carrier family 25 member 4

7.5906

ST6GAL2

ST6 beta-galactoside alpha-2,6-sialyltransferase 2

7.5662

AvBD11

Avian beta defensin 11

7.5066

DOCK5

Dedicator of cytokinesis 5

7.4964

RLN1

Relaxin

7.4939

MMP9

Matrix metallopeptidase 9

7.4666

GGT1

Gamma-glutamyltransferase 1

7.0938

MELTF

Melanotransferrin

6.9221

ID3

Inhibitor of DNA binding 1, HLH protein

6.5950

LOC770617

Transmembrane protein 100-like

6.4296

KIAA1109

Fragile site-associated protein

6.4112

EAF2

ELL associated factor 2

6.0836

ARFGEF3

ARFGEF family member 3

5.8841

HOMER1

Homer scaffolding protein 1

5.6404

GPX3

Glutathione peroxidase 3

5.6046

SLC1A4

Solute carrier family 1 member 4

5.5812

LOC419409

Golgi integral membrane protein 4-like

5.4493

  1. Transcripts from the magnum of layers and non-layers were aligned to the chicken genome and mapped genes with at least a 3-fold change difference and Benjamini Hochberg q-value < 0.05 were considered differentially expressed. DEGs, differentially expressed genes