Table 3 Top 15 enriched pathways associated with differentially expressed homoeologous genes related to metabolism in herbivorous diet group compared with carnivorous diet group
Pathway in intestine transcriptome | Gene NO. | Reference NO. | P value | Pathway ID |
Biosynthesis of antibiotics | 109 | 459 | 1.43E-13 | ko01130 |
PPAR signaling pathway | 40 | 134 | 1.13E-08 | ko03320 |
Carbon metabolism | 59 | 240 | 1.60E-08 | ko01200 |
Steroid biosynthesis | 19 | 40 | 2.02E-08 | ko00100 |
Fat digestion and absorption | 27 | 75 | 3.65E-08 | ko04975 |
Biosynthesis of secondary metabolites | 138 | 757 | 4.06E-08 | ko01110 |
Cholesterol metabolism | 33 | 111 | 2.36E-07 | ko04979 |
Glycine, serine and threonine metabolism | 28 | 86 | 2.39E-07 | ko00260 |
Cysteine and methionine metabolism | 28 | 87 | 3.14E-07 | ko00270 |
Biosynthesis of amino acids | 42 | 165 | 6.80E-07 | ko01230 |
Fatty acid biosynthesis | 15 | 34 | 2.06E-06 | ko00061 |
Proximal tubule bicarbonate reclamation | 19 | 53 | 4.09E-06 | ko04964 |
Protein digestion and absorption | 53 | 244 | 5.08E-06 | ko04974 |
Glycolysis / Gluconeogenesis | 32 | 129 | 2.46E-05 | ko00010 |
Citrate cycle (TCA cycle) | 19 | 62 | 5.23E-05 | ko00020 |
Pathway in liver transcriptome | Gene NO. | Reference NO. | P value | Pathway ID |
Biosynthesis of antibiotics | 80 | 459 | 2.85E-15 | ko01130 |
Metabolic pathways | 257 | 2479 | 8.47E-14 | ko01100 |
Biosynthesis of secondary metabolites | 103 | 757 | 4.59E-12 | ko01110 |
Steroid biosynthesis | 16 | 40 | 2.40E-09 | ko00100 |
Glycine, serine and threonine metabolism | 22 | 86 | 4.08E-08 | ko00260 |
FoxO signaling pathway | 47 | 303 | 7.83E-08 | ko04068 |
Insulin signaling pathway | 49 | 323 | 8.44E-08 | ko04910 |
Cysteine and methionine metabolism | 21 | 87 | 2.42E-07 | ko00270 |
PPAR signaling pathway | 27 | 134 | 2.68E-07 | ko03320 |
Cholesterol metabolism | 24 | 111 | 3.14E-07 | ko04979 |
AMPK signaling pathway | 44 | 298 | 8.28E-07 | ko04152 |
Terpenoid backbone biosynthesis | 14 | 46 | 1.24E-06 | ko00900 |
Glyoxylate and dicarboxylate metabolism | 17 | 68 | 1.99E-06 | ko00630 |
Carbon metabolism | 35 | 240 | 1.43E-05 | ko01200 |
Adipocytokine signaling pathway | 27 | 169 | 2.64E-05 | ko04920 |