Fig. 1

Let U (white), D (green), C (cyan), B (yellow), A (brown) be pseudoclones with prevalence values: 1.0≥u>d>c>b>a>0 respectively. The top row shows 4 possible evolution trees where the time axis is the molecular clock. The bottom row shows the single time-point “fishplot” as appropriately stacked disks. Notice that the leftmost phylogeny suggests that there exist some cells/virion with both A and B alterations while all the other three suggest that there exists no such cell/virion