Fig. 6

Effect of mutations in candidate motifs on gene expression level. For every candidate motif ((a) hexamers; (b) consensus motifs) the difference of gene expression of allelic variants of every gene containing it was compared. Allelic variants as present in different Arabidopsis accessions were grouped into two sets of variants: 1) motif present as defined, 2) motif locus found with at least one mutation. Distributions show effect sizes (Cohen’s d) of differences across all genes with two such allele-groups as present in the different Arabidopsis thaliana accessions based on available RNA-seq expression data. Upper row shows all effect sizes, lower row only for those gene, for which the allelic expression difference was significant (t-test, p-value< 0.05 without correction for multiple testing as the goal was not to identify true-positives, but to apply a filter that imposes some level of significance of difference). For further summary statistics, see Table 4