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Table 3 Enriched and depleted GO-terms in gene sets harboring the identified consensus intron motifs in their first introns. For every GO-term, significant FDR-corrected p-values (pFDR< 0.05) based on Fisher exact tests are listed (correction per GO-category) or left empty if pFDR>0.05

From: Identification of cis-regulatory motifs in first introns and the prediction of intron-mediated enhancement of gene expression in Arabidopsis thaliana

GO- category

GO-term

ACYCYRA

ARATCGA

GATTCG

TTTCGA

KCGAGAR

component

enriched

     

cytosol

1.16E-06

2.08E-07

6.42E-05

3.66E-03

5.21E-05

Golgi apparatus

 

6.10E-07

1.61E-04

3.72E-02

 

endoplasmatic reticulum

 

5.56E-03

2.41E-02

  

nucleus

2.78E-12

   

2.49E-02

depleted

     

mitochondria

8.15E-04

1.04E-02

2.41E-02

4.17E-02

2.49E-02

extracellular

1.84E-12

1.11E-14

5.44E-14

8.27E-13

5.92E-11

chloroplast

4.12E-02

6.09E-04

1.34E-02

 

3.16E-02

function

enriched

     

protein binding

7.47E-11

3.69E-07

1.12E-04

1.81E-05

1.19E-4

structural molecule activity

 

1.36E-03

1.56E-02

3.44E-04

 

DNA or RNA binding

8.06E-05

8.31E-03

2.64E-02

  

depleted

     

unknown molecular function

7.47E-11

2.45E-09

4.30E-04

7.35E-11

2.81E-05

transcription factor activity

 

1.68E-03

2.64E-02

1.54E-02

 

process

enriched

     

DNA or RNA metabolism

3.65E-06

1.82E-04

 

6.25E-04

8.49E-04

cell organisation

4.84E-03

3.27E-04

 

3.64E-02

1.29E-02

transport

 

3.39E-03

1.79E-02

6.21E-04

4.78E-02

depleted

     

unknown processes

6.93E-11

7.53E-10

2.07E-03

1.24E-06

8.49E-04

signal transduction

 

1.13E-02

1.79E-02

7.91E-03

1.53E-02