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Table 2 Enrichment analysis using Statistical Overrepresentation Test (PANTHER 14.1) on genes positively correlated to dimension-1 of PCA and associated to endometrial luminal and glandular epithelial cells (LE, GE); GO terms are provided following PANTHER classification

From: Analysis of the transcriptome of bovine endometrial cells isolated by laser micro-dissection (1): specific signatures of stromal, glandular and luminal epithelial cells

Panther Classification

fold Enrichment

FDR

genes

PANTHER GO biological process complete

 epithelial cell differentiation (GO:0030855)

5.59

1.39E-04

CLDN3, SYNE4, LRP2, F2RL1,DLX6, ELF3, SPINT1, PHGDH, OVOL1, TACSTD2, ST14, EHF, MSX1, EPCAM, ST14, KDF1, IRF6, TJP3, HNF1B, SLC44A4, RAB25, DSP, MCOLN3

 epithelium development (GO:0060429)

3.87

2.05E-04

 cell adhesion (GO:0007155)

3.19

5.76E-02

CLDN3, AZGP1, DSG2, PERP, FOLR1, FOLR1, SPAG6, EPCAM, CLDN7, CLDN4, CXADR, TJP3, IGSF5, CDH1, ITGB6, DSP

PANTHER Protein Class

 tight junction (PC00214), cell junction protein (PC00070)

15.64

1.96E-03

CLDN3, CLDN8, CLDN7, CLDN4, TJP3

 secondary carrier transporter (PC00258), transporter (PC00227)

8.55

2.11E-06

SLC13A5, SLC44A3, SLC5A11, SLC5A11, SLC39A2, SLC27A6, SLC7A4, SLC5A1, SLC27A2, SLC34A2, SLC44A4, SLC5A8

PANTHER Pathways

 Serine glycine biosynthesis (P02776)

44.23

1.65E-02

PSAT1, PHGDH