Table 4 Gene Functional Classification Result (PANTHER 14.1) of over-expressed genes in GE cells from SNEB animals. Main pathways and ontology annotation groups enriched are shown (over-representation statistical test)
PANTHER Classification | fold Enrichment | FDR | genes |
|---|---|---|---|
PANTHER Pathways | |||
 Inflammation mediated by chemokine and cytokine signaling pathway (P00031) | 24.95 | 9.01E-04 | JUNB, CCL2, CCL4, CCL3 |
 Gonadotropin-releasing hormone receptor pathway (P06664) | 31.19 | 3.17E-05 | JUNB, FOS, ATF3, NR4A1 |
 Apoptosis signaling pathway (P00006) | 37.42 | 2.83E-03 | FOS, ATF3 |
PANTHER GO-Slim Biological Process | |||
 chemokine-mediated signaling pathway (GO:0070098) | > 100 | 5.44E-04 | JUNB, CCL2, CCL4, CCL3 |
PANTHER Molecular Function | |||
 DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981) | 21.8 | 2.30E-04 | JUNB, FOS, ATF3, EGR2 |
 cytokine receptor binding (GO:0005126) | 36.04 | 1.75E-03 | CCL2, CCL4, CCL3 |