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Fig. 2 | BMC Genomics

Fig. 2

From: Exposure to hypoxia causes stress erythropoiesis and downregulates immune response genes in spleen of mice

Fig. 2

RNA-seq expression profile of spleen exposed to hypoxia. a Principal component analysis (PCA) of gene expression. b Venn diagram for genes overlapping among five DEG sets (top). The DEGs number in each hypoxia group (bottom). c Clusters obtained via the soft clustering method for 739 DEGs of spleen during hypoxia. d and e Enrichment map of GO terms. Nodes and edges represent GO BP terms and associations between two terms respectively. GO, Gene Ontology; BP, Biological Process; (d for cluster 1–3 and e for cluster 4 in Fig. 2c). f Double immunostaining for PCNA (green) and CD71 (red) on paraffin sections of spleen (× 40, bar = 100 μm)

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BMC Genomics

ISSN: 1471-2164

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