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Fig. 2 | BMC Genomics

Fig. 2

From: Downregulated luteolytic pathways in the transcriptome of early pregnancy bovine corpus luteum are mimicked by interferon-tau in vitro

Fig. 2

Functional pathway enrichment of DEGs in day 18 P compared to NP bovine CL. (A) Pathway enrichment analysis was performed using Metascape and IPA on both up- and downregulated DEGs. The significantly (padj < 0.05) enriched canonical pathways in both tools are represented in a Venn diagram. (B) A dot plot of selected significantly enriched pathways from IPA analysis that were down-regulated in P compared to NP (padj < 0.05; Z-score < − 1.9). The x-axis represents the –log padj. The color indicates the Z-score (a Z-score below − 2 indicates that the pathway is significantly downregulated). The size of the dots represents the gene ratio (the number of genes in the pathway that were significantly differentially expressed relative to the number of genes in the pathway)

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