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Fig. 6 | BMC Genomics

Fig. 6

From: Integrated proteomic and transcriptomic profiling identifies aberrant gene and protein expression in the sarcomere, mitochondrial complex I, and the extracellular matrix in Warmblood horses with myofibrillar myopathy

Fig. 6

Immunofluorescent staining of cross-sections of a myofiber in gluteal muscle from an MFM WB and a control horse. Bar = 10 μm A. Disorganized pattern of CSRP3 staining in the myoplasm of an MFM horse compared to the control horse. B. Desmin aggregates in an MFM horse. C. Merged image showing colocalization of aggregates of desmin and CSRP3 (orange) in an MFM horse. Colocalization with CSRP3 occurred in some but not all fibers with desmin aggregates. D. Normal pattern of CSRP3 staining in a control horses taken at the same exposure as A. E. Normal pattern of desmin staining in a control horses taken at the same exposure as B. F. Merged desmin and CSRP3 stains in a control horse

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BMC Genomics

ISSN: 1471-2164

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