Fig. 4
The connectivity of PPI networks constructed by DEGs at the ith round of rectification. The data of four groups (ModT, Two-way rectification using ModT, Min-Edge, Two-way rectification using Min-Edge) are divided into two comparisons (ModT vs Two-way rectification using ModT, Min-Edge vs Two-way rectification using Min-Edge). The x-axis represents the number of DEGs generated at the ith round (i=1, 2,..., 8) of rectification, while the y-axis represents the number of genes in the giant connected component of the PPI network constructed by these DEGs obtained through each round of rectification. The value of n represents the number of initial value of start genes of the two-way rectification method, while the m represents the ratio of DEGs that can be extended by the two-way rectification method at each round of rectification. a depicts the results at m=0.1 and n=20 between these methods. b depicts the results at m=0.1 and n=50 between these methods. c depicts the results at m=0.05 and n=20 of two comparisons. d depicts the results at m=0.05 and n=50 of two comparisons. Purple line: the result of the ModT method. Blue line: the result of the two-way rectification of which the start gene list is selected from ModT method. Red line: the result of the two-way rectification of which its initial gene list is selected from Min-Edge method. Yellow line: the result of the Min-Edge method