The genomes of precision edited cloned calves show no evidence for off-target events or increased de novo mutagenesis

Table 1 Number of candidate de novo mutations identified after each filter was applied to 31,190 filtered variants across the three control cloned calves and two gene-edited cloned calves

			Heterozygousde novomutations		Mosaicde novomutations
Sample ID	Unique to each sample	Map quality = 60	Candidate de novo	Likely de novo	Candidate de novo	Likely de novo
1802	1,224	439	340	205	45	16
1803	1,402	550	409	276	82	14
1804	2,769	686	566	293	67	9
1805	1,145	433	313	197	52	8
B071	1,470	587	408	277	133	11

ISSN: 1471-2164