Skip to main content

Table 4 Selected differentially expressed proteins in duodenum mucosa caused by pantothenic acid deficiency

From: Severe pantothenic acid deficiency induces alterations in the intestinal mucosal proteome of starter Pekin ducks

UniProtKB ID

Protein name

Short name

Fold change*

P-Value

Glycolysis and gluconeogenesis

 U3IHG8

Fructose-bisphosphate aldolase

ALDOB

−5.47

5.90E-09

 U3IVG9

Hexokinase domain containing 1

HKDC1

−4.34

1.13E-13

 U3IR52

Alpha-enolase

ENO1

−3.75

6.19E-08

 U3J2H8

Fructose-bisphosphatase 1

FBP1

−2.42

1.35E-10

 U3J1L1

Glyceraldehyde-3-phosphate dehydrogenase

GAPDH

−3.02

9.49E-06

 U3I0F9

Pyruvate kinase

PKM

−3.28

1.94E-07

 U3IZA5

ATP-dependent 6-phosphofructokinase

PFKP

−2.33

3.93E-05

 U3I8D8

Triosephosphate isomerase

TPI1

−2.93

9.45E-05

 U3ILF5

Phosphoglycerate kinase

PGK1

−2.01

1.71E-06

 U3IR48

Dihydrolipoyl dehydrogenase

DLD

−1.66

2.09E-02

 U3IEW2

Pyruvate dehydrogenase E1 beta subunit

PDHB

− 1.58

1.79E-02

 U3I939

Fructose-bisphosphate aldolase

ALDOA

1.89

1.34E-03

 U3IR68

Hexokinase 1

HK1

3.31

1.12E-02

Fatty acid beta oxidation

 U3J4Z9

Acyl-CoA synthetase long chain family member 5

ACSL5

−3.06

6.74E-09

 U3I9A1

Acyl-CoA dehydrogenase family member 11

ACAD11

−1.96

1.34E-02

 U3ITA9

Medium-chain specific acyl-CoA dehydrogenase

ACADM

−1.85

1.79E-05

 U3IHS8

Carnitine O-acetyltransferase

CRAT

−1.78

6.54E-03

 U3IR48

Dihydrolipoyl dehydrogenase

DLD

−1.66

2.09E-02

 U3I6S1

Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

HADHB

−1.65

1.60E-03

 U3IEF4

Enoyl-CoA delta isomerase 2

ECI2

−1.65

4.61E-02

 U3J928

Acyl-coenzyme A oxidase

ACOX1

−1.51

1.68E-05

 U3IDQ1

Acyl-coenzyme A oxidase

ACOX2

−1.74

3.50E-05

TCA cycle

 U3IR48

Dihydrolipoyl dehydrogenase

DLD

−1.66

2.09E-02

 R0J775

Aconitase 1 (Fragment)

ACO1

−1.64

2.75E-10

 U3IC15

Aconitate hydratase, mitochondrial

ACO2

−2.13

9.22E-11

 R0JXM5

Malate dehydrogenase (Fragment)

MDH1

−1.78

2.25E-05

 U3IA60

Malate dehydrogenase

MDH2

−2.89

4.45E-08

 U3IEW2

Pyruvate dehydrogenase E1 beta subunit

PDHB

−1.58

1.79E-02

 U3J597

Isocitrate dehydrogenase [NADP]

IDH1

1.58

5.05E-06

Oxidative phosphorylation

 U3J532

NADH:ubiquinone oxidoreductase subunit A5

NDUFA5

−1.58

1.94E-02

 R0LLX6

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Fragment)

NDUFA6

−1.56

4.97E-02

 U3J175

ATP synthase, H+ transporting, mitochondrial Fo complex subunit B1

ATP5F1

−1.80

2.12E-03

 R0LYJ7

ATP synthase subunit d, mitochondrial (Fragment)

ATP5H

−1.79

2.69E-04

 R0LIL9

ATP synthase subunit O, mitochondrial (Fragment)

ATP5O

−1.60

2.16E-03

Regulation of actin cytoskeleton

 U3IFN5

Villin 1

VIL1

−3.12

1.13E-08

 U3IY96

Ezrin

EZR

−2.00

1.61E-05

 U3IRY0

Vimentin

VIM

2.66

5.54E-04

 U3J6G2

Tropomyosin 3

TPM3

4.51

1.36E-02

 U3I7J8

Tropomyosin alpha-1 chain

TPM1

9.58

6.76E-04

 U3IA79

Myosin light chain 1

MYL1

11.47

2.50E-06

 R0LM85

Myosin light chain kinase (Fragment)

MYLK

2.88

1.83E-02

 U3I4I9

Actinin alpha 1

ACTN1

2.13

5.89E-07

 U3IZ83

Fibronectin 1

FN1

2.28

4.31E-02

 U3IR26

Vinculin

VCL

1.87

4.54E-11

 U3I935

Moesin

MSN

2.07

5.48E-03

Oxidative stress

 U3J0T0

Amine oxidase

MAOA

−2.56

5.04E-08

 A0A172QNN4

Catalase

CAT

−1.84

1.49E-05

 R0JZP2

Microsomal glutathione S-transferase 1 (Fragment)

MGST1

−1.57

2.66E-02

 U3I5T1

Glutamate-cysteine ligase catalytic subunit

GCLC

1.57

9.62E-03

Intestinal absorption

 U3IRP7

Solute carrier family 2 member 2

SLC2A2

−5.11

3.17E-02

 U3IFN5

Villin 1

VIL1

−3.12

1.13E-08

 U3IY96

Ezrin

EZR

−2.00

1.61E-05

 U3IUS6

Monoacylglycerol O-acyltransferase 2

MOGAT2

−2.28

5.35E-03

  1. TCA, tricarboxylic acid
  2. * Fold change is expressed as the ratio of the pantothenic acid-deficient to the control group. For the down-regulated proteins, the fold change was transformed to the corresponding negative value