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Table 3 Total and concentration-dependent immunoretained H. curtus venom proteins by heterologous antivenoms

From: Venom-gland transcriptomic, venomic, and antivenomic profiles of the spine-bellied sea snake (Hydrophis curtus) from the South China Sea

Fractions   50 100 150 300 600 Toxins
1 μg Total 16.56 33.13 49.69 99.38 198.77 3-FTx (SNX)
μg RET-Bm 0.95 2.94 1.18 4.17 1.82
μg RET-Na 16.56 26.48 34.36 25.62 31.13
2 μg Total 2.31 4.61 6.92 13.84 27.69 3-FTx (LNX)
μg RET-Bm 2.14 4.61 6.92 13.84 24.66
μg RET-Na 2.31 4.61 6.92 10.39 17.71
3 μg Total 1.14 2.29 3.43 6.86 13.73 3-FTx (LNX)
μg RET-Bm 1.14 2.26 3.43 6.86 12.40
μg RET-Na 1.14 2.29 3.43 5.37 8.16
4 μg Total 0.17 0.34 0.50 1.01 2.01 3-FTx (LNX)
μg RET-Bm 0.17 0.34 0.50 1.01 2.01
μg RET-Na 0.17 0.34 0.48 0.92 0.93
5 μg Total 2.05 4.10 6.15 12.3 24.6 PLA2 + 3-FTx (LNX)
μg RET-Bm 0.81 1.38 1.53 4.03 3.73
μg RET-Na 1.04 2.16 2.15 4.03 4.02
6 μg Total 4.95 9.90 14.84 29.69 59.37 PLA2
μg RET-Bm 3.44 4.42 5.48 11.17 9.69
μg RET-Na 4.44 7.41 8.59 11.71 14.67
7 μg Total 0.43 0.85 1.28 2.56 5.12 PLA2 + 3-FTx (LNX)
μg RET-Bm 0.43 0.85 1.28 2.56 1.71
μg RET-Na 0.43 0.85 1.28 2.56 1.24
8 μg Total 17.48 34.96 52.44 104.87 209.75 PLA2
μg RET-Bm 14.79 20.02 21.4 31.55 22.51
μg RET-Na 15.03 30.25 35.92 44.18 48.59
9 μg Total 0.40 0.79 1.19 2.38 4.77 PLA2
μg RET-Bm 0.13 0.23 0.47 0.92 0.46
μg RET-Na 0.40 0.56 0.69 1.73 1.01
10 μg Total 0.16 0.33 0.49 0.99 1.98 PLA2
μg RET-Bm 0.11 0.33 0.20 0.87 0.62
μg RET-Na 0.16 0.33 0.42 0.99 0.69
11 μg Total 4.35 8.70 13.05 26.11 52.22 CRISP
μg RET-Bm 2.63 5.74 10.06 14.72 26.34
μg RET-Na 3.59 7.66 10.13 24.57 39.14
  1. RET immunoretained, Bm B. multicintus antivenom, Na N. atra antivenom