Venom-gland transcriptomic, venomic, and antivenomic profiles of the spine-bellied sea snake (Hydrophis curtus) from the South China Sea

Table 3 Total and concentration-dependent immunoretained H. curtus venom proteins by heterologous antivenoms

Fractions		50	100	150	300	600	Toxins
1	μg Total	16.56	33.13	49.69	99.38	198.77	3-FTx (SNX)
	μg RET-Bm	0.95	2.94	1.18	4.17	1.82
	μg RET-Na	16.56	26.48	34.36	25.62	31.13
2	μg Total	2.31	4.61	6.92	13.84	27.69	3-FTx (LNX)
	μg RET-Bm	2.14	4.61	6.92	13.84	24.66
	μg RET-Na	2.31	4.61	6.92	10.39	17.71
3	μg Total	1.14	2.29	3.43	6.86	13.73	3-FTx (LNX)
	μg RET-Bm	1.14	2.26	3.43	6.86	12.40
	μg RET-Na	1.14	2.29	3.43	5.37	8.16
4	μg Total	0.17	0.34	0.50	1.01	2.01	3-FTx (LNX)
	μg RET-Bm	0.17	0.34	0.50	1.01	2.01
	μg RET-Na	0.17	0.34	0.48	0.92	0.93
5	μg Total	2.05	4.10	6.15	12.3	24.6	PLA₂ + 3-FTx (LNX)
	μg RET-Bm	0.81	1.38	1.53	4.03	3.73
	μg RET-Na	1.04	2.16	2.15	4.03	4.02
6	μg Total	4.95	9.90	14.84	29.69	59.37	PLA₂
	μg RET-Bm	3.44	4.42	5.48	11.17	9.69
	μg RET-Na	4.44	7.41	8.59	11.71	14.67
7	μg Total	0.43	0.85	1.28	2.56	5.12	PLA₂ + 3-FTx (LNX)
	μg RET-Bm	0.43	0.85	1.28	2.56	1.71
	μg RET-Na	0.43	0.85	1.28	2.56	1.24
8	μg Total	17.48	34.96	52.44	104.87	209.75	PLA₂
	μg RET-Bm	14.79	20.02	21.4	31.55	22.51
	μg RET-Na	15.03	30.25	35.92	44.18	48.59
9	μg Total	0.40	0.79	1.19	2.38	4.77	PLA₂
	μg RET-Bm	0.13	0.23	0.47	0.92	0.46
	μg RET-Na	0.40	0.56	0.69	1.73	1.01
10	μg Total	0.16	0.33	0.49	0.99	1.98	PLA₂
	μg RET-Bm	0.11	0.33	0.20	0.87	0.62
	μg RET-Na	0.16	0.33	0.42	0.99	0.69
11	μg Total	4.35	8.70	13.05	26.11	52.22	CRISP
	μg RET-Bm	2.63	5.74	10.06	14.72	26.34
	μg RET-Na	3.59	7.66	10.13	24.57	39.14

ISSN: 1471-2164