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Table 1 The seven CpGs on VTRNA2-1 with the largest differences in methylation between term and preterm samples (n = 10)

From: Elevated methylation of the vault RNA2-1 promoter in maternal blood is associated with preterm birth

Target ID† CHR Position Functional location Mean β value in term samples (n = 5) Mean β value in preterm samples (n = 5) Difference* p-valuea q-valueb
cg26328633 5 135,416,394 TSS200 0.125 0.520 0.395 0.014 0.050
cg25340688 5 135,416,398 TSS200 0.121 0.508 0.387 0.014 0.050
cg06536614 5 135,416,381 TSS200 0.129 0.492 0.363 0.020 0.050
cg00124993 5 135,416,412 TSS200 0.114 0.471 0.357 0.014 0.050
cg26896946 5 135,416,405 TSS200 0.192 0.503 0.311 0.013 0.050
cg04481923 5 135,416,205 1stExon;3’UTR 0.122 0.389 0.267 0.015 0.050
cg18678645 5 135,416,331 TSS200 0.115 0.376 0.261 0.051 0.050
  1. Gene ID of VTRNA2-1 is 100,126,299
  2. CHR Chromosome
  3. aMann–Whitney U-test, p < 0.05
  4. bThe false discovery rate (FDR) was controlled using the Benjamini–Hochberg correction (q < 0.05)
  5. †Name of the probe
  6. *Difference between mean β values of preterm births and term births