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Table 2 Clinical characteristics of the study groups (n = 82)

From: Elevated methylation of the vault RNA2-1 promoter in maternal blood is associated with preterm birth

 

Term (≥ 37, n = 39)

Preterm (< 37, n = 43)

p-value

Mean ± SD

Mean ± SD

Maternal age

31.7 ± 2.8

30.9 ± 4.6

0.418

BMI at delivery

25.9 ± 3.3

24.1 ± 4.2

0.037a

Gravidity

  

0.471

 0

16 (41.0)

15 (34.9)

 

 1

23 (59.0)

28 (65.1)

 

Parity

  

0.118

 Nulliparous

22 (56.4)

22 (51.2)

 

 Multiparous

17 (43.6)

21 (48.8)

 

Delivery season

  

0.021*

 Spring, n (%)

5 (12.8)

12 (27.9)

 

 Summer, n (%)

3 (7.7)

11 (25.6)

 

 Autumn, n (%)

19 (48.7)

13 (30.2)

 

 Winter, n (%)

12 (30.8)

7 (16.3)

 

Mode of delivery

  

0.599

 Vaginal, n (%)

24 (61.5)

24 (55.8)

 

 C-section, n (%)

15 (38.5)

19 (44.2)

 

Education (n = 68)

  

0.096

 Below high school

8 (20.5)

13 (44.8)

 

 College or more

31 (79.5)

16 (55.2)

 

Gestational age

39.4 ± 1.0

29.1 ± 2.8

<0.001a

White blood cell, (x103 cells/μL)

10.10 ± 3.00

12.21 ± 3.83

0.008 a

Granulocyte, (%)

74.65 ± 7.44

77.81 ± 7.01

0.066

Lymphocyte, (%)

18.01 ± 5.78

21.55 ± 34.72

0.548

Monocyte, (%)

6.86 ± 2.01

5.81 ± 1.76

0.021 a

Mycoplasma

  

0.702

 Positive, n (%)

2 (5.4)

3 (8.6)

 

 Negative, n (%)

35 (94.6)

32 (91.4)

 

Ureaplasma (n = 72)

  

<0.001*

 Positive, n (%)

0 (0.0)

13 (37.1)

 

 Negative, n (%)

37 (100.0)

22 (62.9)

 

Chorioamnionitis (n = 67)

  

<0.001*

 Positive, n (%)

0 (5.1)

17 (56.7)

 

 Negative, n (%)

37 (100)

13 (43.3)

 

Birth weight

3310.5 ± 394.7

1385.7 ± 504.1

<0.001a

Sex

  

0.654

 Male, n (%)

20 (51.3)

24 (55.8)

 

 Female, n (%)

19 (48.7)

19 (44.2)

 

Apgar 1 min

9.5 ± 0.8

5.9 ± 2.4

<0.001a

Apgar 5 min

9.9 ± 0.2

7.5 ± 2.1

<0.001a

  1. Data are shown as the mean ± SD for continuous variables and as n (%) for categorical data
  2. BMI body mass index
  3. aStudent’s t-test
  4. *χ2 test