From: Elevated methylation of the vault RNA2-1 promoter in maternal blood is associated with preterm birth
 | Term (≥ 37, n = 39) | Preterm (< 37, n = 43) | p-value |
---|---|---|---|
Mean ± SD | Mean ± SD | ||
Maternal age | 31.7 ± 2.8 | 30.9 ± 4.6 | 0.418 |
BMI at delivery | 25.9 ± 3.3 | 24.1 ± 4.2 | 0.037a |
Gravidity | Â | Â | 0.471 |
 0 | 16 (41.0) | 15 (34.9) |  |
 1 | 23 (59.0) | 28 (65.1) |  |
Parity | Â | Â | 0.118 |
 Nulliparous | 22 (56.4) | 22 (51.2) |  |
 Multiparous | 17 (43.6) | 21 (48.8) |  |
Delivery season | Â | Â | 0.021* |
 Spring, n (%) | 5 (12.8) | 12 (27.9) |  |
 Summer, n (%) | 3 (7.7) | 11 (25.6) |  |
 Autumn, n (%) | 19 (48.7) | 13 (30.2) |  |
 Winter, n (%) | 12 (30.8) | 7 (16.3) |  |
Mode of delivery | Â | Â | 0.599 |
 Vaginal, n (%) | 24 (61.5) | 24 (55.8) |  |
 C-section, n (%) | 15 (38.5) | 19 (44.2) |  |
Education (n = 68) | Â | Â | 0.096 |
 Below high school | 8 (20.5) | 13 (44.8) |  |
 College or more | 31 (79.5) | 16 (55.2) |  |
Gestational age | 39.4 ± 1.0 | 29.1 ± 2.8 | <0.001a |
White blood cell, (x103 cells/μL) | 10.10 ± 3.00 | 12.21 ± 3.83 | 0.008 a |
Granulocyte, (%) | 74.65 ± 7.44 | 77.81 ± 7.01 | 0.066 |
Lymphocyte, (%) | 18.01 ± 5.78 | 21.55 ± 34.72 | 0.548 |
Monocyte, (%) | 6.86 ± 2.01 | 5.81 ± 1.76 | 0.021 a |
Mycoplasma | Â | Â | 0.702 |
 Positive, n (%) | 2 (5.4) | 3 (8.6) |  |
 Negative, n (%) | 35 (94.6) | 32 (91.4) |  |
Ureaplasma (n = 72) | Â | Â | <0.001* |
 Positive, n (%) | 0 (0.0) | 13 (37.1) |  |
 Negative, n (%) | 37 (100.0) | 22 (62.9) |  |
Chorioamnionitis (n = 67) | Â | Â | <0.001* |
 Positive, n (%) | 0 (5.1) | 17 (56.7) |  |
 Negative, n (%) | 37 (100) | 13 (43.3) |  |
Birth weight | 3310.5 ± 394.7 | 1385.7 ± 504.1 | <0.001a |
Sex | Â | Â | 0.654 |
 Male, n (%) | 20 (51.3) | 24 (55.8) |  |
 Female, n (%) | 19 (48.7) | 19 (44.2) |  |
Apgar 1 min | 9.5 ± 0.8 | 5.9 ± 2.4 | <0.001a |
Apgar 5 min | 9.9 ± 0.2 | 7.5 ± 2.1 | <0.001a |