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Table 2 Clinical characteristics of the study groups (n = 82)

From: Elevated methylation of the vault RNA2-1 promoter in maternal blood is associated with preterm birth

  Term (≥ 37, n = 39) Preterm (< 37, n = 43) p-value
Mean ± SD Mean ± SD
Maternal age 31.7 ± 2.8 30.9 ± 4.6 0.418
BMI at delivery 25.9 ± 3.3 24.1 ± 4.2 0.037a
Gravidity    0.471
 0 16 (41.0) 15 (34.9)  
 1 23 (59.0) 28 (65.1)  
Parity    0.118
 Nulliparous 22 (56.4) 22 (51.2)  
 Multiparous 17 (43.6) 21 (48.8)  
Delivery season    0.021*
 Spring, n (%) 5 (12.8) 12 (27.9)  
 Summer, n (%) 3 (7.7) 11 (25.6)  
 Autumn, n (%) 19 (48.7) 13 (30.2)  
 Winter, n (%) 12 (30.8) 7 (16.3)  
Mode of delivery    0.599
 Vaginal, n (%) 24 (61.5) 24 (55.8)  
 C-section, n (%) 15 (38.5) 19 (44.2)  
Education (n = 68)    0.096
 Below high school 8 (20.5) 13 (44.8)  
 College or more 31 (79.5) 16 (55.2)  
Gestational age 39.4 ± 1.0 29.1 ± 2.8 <0.001a
White blood cell, (x103 cells/μL) 10.10 ± 3.00 12.21 ± 3.83 0.008 a
Granulocyte, (%) 74.65 ± 7.44 77.81 ± 7.01 0.066
Lymphocyte, (%) 18.01 ± 5.78 21.55 ± 34.72 0.548
Monocyte, (%) 6.86 ± 2.01 5.81 ± 1.76 0.021 a
Mycoplasma    0.702
 Positive, n (%) 2 (5.4) 3 (8.6)  
 Negative, n (%) 35 (94.6) 32 (91.4)  
Ureaplasma (n = 72)    <0.001*
 Positive, n (%) 0 (0.0) 13 (37.1)  
 Negative, n (%) 37 (100.0) 22 (62.9)  
Chorioamnionitis (n = 67)    <0.001*
 Positive, n (%) 0 (5.1) 17 (56.7)  
 Negative, n (%) 37 (100) 13 (43.3)  
Birth weight 3310.5 ± 394.7 1385.7 ± 504.1 <0.001a
Sex    0.654
 Male, n (%) 20 (51.3) 24 (55.8)  
 Female, n (%) 19 (48.7) 19 (44.2)  
Apgar 1 min 9.5 ± 0.8 5.9 ± 2.4 <0.001a
Apgar 5 min 9.9 ± 0.2 7.5 ± 2.1 <0.001a
  1. Data are shown as the mean ± SD for continuous variables and as n (%) for categorical data
  2. BMI body mass index
  3. aStudent’s t-test
  4. 2 test