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Table 3 Comparison of specific DNA methylation sites between women with term and preterm births after pyrosequencing

From: Elevated methylation of the vault RNA2-1 promoter in maternal blood is associated with preterm birth

Variable Target ID† of differentially methylated site Term (n = 39) Preterm (n = 43) p-value
VTRNA2-1_pos1 cg04481923 25.8 ± 20.9 33.9 ± 18.6 0.065
VTRNA2-1_pos2   26.3 ± 22.2 35.2 ± 19.5 0.045a
VTRNA2-1_pos3   27.4 ± 22.3 36.4 ± 19.8 0.026a
  1. Data are presented as the mean ± SD
  2. VTRNA2-1_pos1, _pos2, and _pos3 were analyzed by pyrosequencing as CpG sites of chromosome 5:135,416,205, chromosome 5:135,416,207, and chromosome 5:135,416,214, respectively
  3. VTRNA2-1 vault RNA 2 − 1
  4. aMann–Whitney U-test, p < 0.05
  5. †Name of the probe