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Table 3 Comparison of specific DNA methylation sites between women with term and preterm births after pyrosequencing

From: Elevated methylation of the vault RNA2-1 promoter in maternal blood is associated with preterm birth

Variable

Target ID† of differentially methylated site

Term (n = 39)

Preterm (n = 43)

p-value

VTRNA2-1_pos1

cg04481923

25.8 ± 20.9

33.9 ± 18.6

0.065

VTRNA2-1_pos2

 

26.3 ± 22.2

35.2 ± 19.5

0.045a

VTRNA2-1_pos3

 

27.4 ± 22.3

36.4 ± 19.8

0.026a

  1. Data are presented as the mean ± SD
  2. VTRNA2-1_pos1, _pos2, and _pos3 were analyzed by pyrosequencing as CpG sites of chromosome 5:135,416,205, chromosome 5:135,416,207, and chromosome 5:135,416,214, respectively
  3. VTRNA2-1 vault RNA 2 − 1
  4. aMann–Whitney U-test, p < 0.05
  5. †Name of the probe
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BMC Genomics

ISSN: 1471-2164

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