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Table 1 Single nt polymorphisms (SNPs) deduced by comparison of six Tunisian whole genome SARS-CoV-2 sequences with reference SARS-CoV-2 NC045512

From: Whole genome sequencing and phylogenetic analysis of six SARS-CoV-2 strains isolated during COVID-19 pandemic in Tunisia, North Africa

Gene nsp2     nsp 3 nsp4     nsp6 nsp7 nsp8 nsp12  
Nucleotide position 1059 1397 1666 2113 2416 3037 3896 4288 5557 7420 8371 8782 9479 9514 10,046 11,083 11,935 12,555 13,495 14,408 15,324 16,178
Cov0010 SNPs mutations          T > C    C > T        C > T    
Proteins mutations          G946G    S75S        L19F    
Cov0880 SNPs mutations   G > A       G > T      G > T A > G G > A G > T   A > C     
Proteins mutations   V198I       E523D      G309C L320L V498I L37F   E155A     
Cov1339 SNPs mutations     C > T   C > T               C > T   C > T
Proteins mutations     L436L   F105F               P323L   S913L
Cov1663 SNPs mutations       C > T G > T    C > T        A > C    C > T C > T  
Proteins mutations       F105F V393F    I1567I        Q31H    P323L N628N  
Cov0425 SNPs mutations      C > T C > T      G > T          C > T   
Proteins mutations      Y537Y F105F      Q1884H          P323L   
Cov1482 SNPs mutations C > T   T > C    C > T               C > T   
Proteins mutations T85I   F/287F    F105F               P323L   
Gene nsp13 nsp14 nsp15 S Orf3a Orf8 N  
Nucleotide position 17,690 18,523 18,877 19,525 20,032 21,648 22,210 22,397 22,424 22,435 22,468 22,503 23,403 25,411 25,563 27,896 28,144 28,346 28,347 28,835 28,878  
Cov0010 SNPs mutations            G > T       T > C     G > A  
Proteins mutations            T302T       L84S     S202N  
Cov0880 SNPs mutations         T > A       A > C   G > T     T > C   
Proteins mutations         Y279N       I7L   M1I     S188P   
Cov1339 SNPs mutations C > T   C > T G > T    C > T   G > A T > C   A > G A > G   G > T        
Proteins mutations S485L   L280L D496Y    P216L   A288T C291C   Q314R D614G   Q57H        
Cov1663 SNPs mutations   G > T    C > T C > T        A > G          
Proteins mutations   V162L    R138C T29I        D614G          
Cov0425 SNPs mutations              A > G   G > T        
Proteins mutations              D614G   Q57H        
Cov1482 SNPs mutations              A > G   G > T    G > T G > T    
Proteins mutations              D614G   Q57H    G25F G25F    
  1. (In bold and underlined: confirmed mutations with more than 2500 reads. In italics: validated mutations with less than 2500 reads)